dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0039445 | ||||||||
| Uniprot Accession | Q9P7H0; NHP2_SCHPO; O94239; | ||||||||
| Genbank Protein ID | NP_594717.1; | ||||||||
| Genbank Nucleotide ID | NM_001020144.2; | ||||||||
| Protein Name | H/ACA ribonucleoprotein complex subunit 2 | ||||||||
| Protein Synonyms/Alias | H/ACA snoRNP protein NHP2;High mobility group-like nuclear protein 2;P17-nhp2; | ||||||||
| Gene Name | nhp2 | ||||||||
| Gene Synonyms/Alias | SPAC1782.10c; | ||||||||
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) | ||||||||
| NCBI Taxa ID | 284812 | ||||||||
| Functional Description (View all) |
Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. Required for stability of the H/ACA snoRNPs. | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
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| Sequence (Fasta) | MAKDKKDHKH SGSTEDEYDS YLPALMPIAK PLAPKKLNKK MMKTVKKASK QKHILRGVKE 60 VVKAVRKGEK GLVILAGDIS PMDVISHIPV LCEDNNVPYL YTVSKELLGE ASNTKRPTSC 120 VMIVPGGKKK DMSKVEEYKE SYEEIIKEVP ALEV 155 |
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| Keyword | KW-0181--Complete proteome |
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| Interpro | IPR002415--H/ACA_rnp_Nhp2_euk |
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| PROSITE | |||||||||
| Pfam | PF01248--Ribosomal_L7Ae |
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| Gene Ontology | GO:0031429--C:box H/ACA snoRNP complex |