dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0039437
Uniprot Accession Q9P7B4; YI13_SCHPO;
Genbank Protein ID NP_593098.1;
Genbank Nucleotide ID NM_001018495.2;
Protein Name NADP-dependent 3-hydroxy acid dehydrogenase
Protein Synonyms/Alias L-allo-threonine dehydrogenase;
Gene Name SPAC521.03
Gene Synonyms/Alias
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 NADP-dependent dehydrogenase with broad substrate specificity acting on 3-hydroxy acids. Catalyzes the NADP-dependent oxidation of L-allo-threonine to L-2-amino-3-keto-butyrate, which is spontaneously decarboxylated into aminoacetone. Also acts on D-threonine, L-serine, D-serine, D-3-hydroxyisobutyrate, L-3-hydroxyisobutyrate, D-glycerate and L-glycerate.
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
42ILAARRFSTVEEIAKdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
43LAARRFSTVEEIAKEdbPTM 3.0;UniProt18257517; 16381945; 23193290
Sequence
(Fasta)		MSRLDGKTIL ITGASSGIGK STAFEIAKVA KVKLILAARR FSTVEEIAKE LESKYEVSVL 60
PLKLDVSDLK SIPGVIESLP KEFADIDVLI NNAGLALGTD KVIDLNIDDA VTMITTNVLG 120
MMAMTRAVLP IFYSKNKGDI LNVGSIAGRE SYVGGSVYCS TKSALAQFTS ALRKETIDTR 180
IRIMEVDPGL VETEFSVVRF HGDKQKADNV YKNSEPLTPE DIAEVILFAL TRRENVVIAD 240
TLVFPSHQGG ANHVYRKQA
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0520--NAD
KW-0521--NADP
KW-0539--Nucleus
KW-0560--Oxidoreductase
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR002198--DH_sc/Rdtase_SDR
IPR002347--Glc/ribitol_DH
IPR016040--NAD(P)-bd_dom
IPR020904--Sc_DH/Rdtase_CS
PROSITE

PS00061--ADH_SHORT
Pfam

PF00106--adh_short
Gene Ontology

GO:0005829--C:cytosol
GO:0016491--F:oxidoreductase activity