dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0039431
Uniprot Accession Q9P790; VPS72_SCHPO;
Genbank Protein ID NP_595388.1;
Genbank Nucleotide ID NM_001021295.2;
Protein Name SWR complex protein 2
Protein Synonyms/Alias
Gene Name swc2
Gene Synonyms/Alias vps72;SPBP35G2.13c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Participates in the catalytic exchange of histone H2A for the H2A variant pht1, an euchromatin-specific factor, leading to chromatin remodeling and changes in transcription of targeted genes.
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
64DIEISSESSDEEAELdbPTM 3.0;UniProt18257517; 16381945; 23193290
65IEISSESSDEEAELKdbPTM 3.0;UniProt18257517; 16381945; 23193290
Sequence
(Fasta)
MSATESLVAG RTRRANAGNK MRELLEKEHL RMTQQNAEIE KEDEEYNIEE EEEAERDIEI 60
SSESSDEEAE LKKLEEEGEE VEKILRDEER IKKRKIQKNR AANLQRTLQP PKRPTPSAAS 120
EVPKKKYKKI KVDPSARRTS SRMHTVLMAQ STETRLQEAK PRRKYTVSAS ANRQKGTMTQ 180
QQRFEEAAKT EAQNLSSLRN YVHLEEQRRL RLKRNAAKHR QLREPILKFI SKTISTEDGR 240
EASNYYVAPL EHPLCHSAPP LQMPQHRAVE CVITGKPAIY LDPVTQLPIS NVQAFQQVRE 300
VYNQRYSWSA MLNLFH 317
Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro

IPR008895--Vps72/YL1
IPR013272--Vps72/YL1_C

PROSITE
Pfam

PF08265--YL1_C

Gene Ontology

GO:0072686--C:mitotic spindle
GO:0005730--C:nucleolus
GO:0000812--C:Swr1 complex
GO:0043486--P:histone exchange
GO:0006357--P:regulation of transcription from RNA polymerase II promoter