dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0039422 | ||||||||
| Uniprot Accession | Q9P6S5; ASK1_SCHPO; P78949; | ||||||||
| Genbank Protein ID | NP_595657.1; | ||||||||
| Genbank Nucleotide ID | NM_001021551.2; | ||||||||
| Protein Name | DASH complex subunit ask1 | ||||||||
| Protein Synonyms/Alias | Associated with spindles and kinetochores protein 1;Meiotically up-regulated gene 181 protein;Outer kinetochore protein ask1; | ||||||||
| Gene Name | ask1 | ||||||||
| Gene Synonyms/Alias | mug181;SPBC27.02c; | ||||||||
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) | ||||||||
| NCBI Taxa ID | 284812 | ||||||||
| Functional Description (View all) |
Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore. Plays a role in meiosis. | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
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| Sequence (Fasta) | MNNLEQLERL EQSITLALYE IDANFSKCHR TVTTKILPIV EKYAKNCNTI WDSSKFWKQF 60 FEASANVSLS GVEEPVPVES NPSDQDVMSN STEADLQLHT KNEHLEKRHS FVGKSDFPDA 120 AVQGDNTKNE DFVQSTPKKM DVSLEDISLD DAALTPIPAR MQTPLRKPEN NPHTGRSALL 180 HRVLDTNWQV QVTPREPKNL QSQEVMDIDS SPFVSPSPIS MKMDMPSLND RNSSHALSLF 240 AEFEHESYDS INPSGMSPPK TIQFSPHTMG VGSSQQANER SLSLQRKLET LNDSNDSFVK 300 EEDSWEL 308 |
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| Keyword | KW-0131--Cell cycle |
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| Interpro | IPR013964--DASH_Ask1 |
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| PROSITE | |||||||||
| Pfam | PF08655--DASH_Ask1 |
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| Gene Ontology | GO:0000778--C:condensed nuclear chromosome kinetochore |