dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0039403
Uniprot Accession Q9P6H9; REB1_SCHPO; O94422;
Genbank Protein ID NP_595080.1;
Genbank Nucleotide ID NM_001020986.2;
Protein Name DNA-binding protein reb1
Protein Synonyms/Alias
Gene Name reb1
Gene Synonyms/Alias SPBC1198.11c;SPBC660.01c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 DNA-binding protein that recognizes sites within both the enhancer and the promoter of rRNA transcription, as well as upstream of many genes transcribed by RNA polymerase II. Has a role in the termination of RNA polymerase I catalyzed transcription.
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
56GSIEPKFSPALSIKEdbPTM 3.0;SysPTM 2.0;curated18257517; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)		MDTSVLNPEL QIHGFIGVDS LQSSRKRKND FDDFPLNKGL KTNNNDYSGS IEPKFSPALS 60
IKEDGKNDRN FEALMSLQAQ DSNLSEQNTS IHLDALASSS IALGNDNVDS SAFLSKVNKG 120
VNAMRNSTSN QTNDSILISP SEITNMDPFL KGSARWTAEH WDYLERRMQN FCQTYSLDHT 180
QVADSLHEKR LHGPLSSLVK LLVQEMPSFT RRTILRHLRA LYNIPGYEKY SRKNSSGRGD 240
FGVQETAIIS QEVHNFIMDQ GWSEYQFCNQ IWAGKCPKTI RMFYSNLYKK LSHRDAKSIY 300
HHVRRAYNPF EDRCVWSKEE DEELRKNVVE HGKCWTKIGR KMARMPNDCR DRWRDVVRFG 360
DKLKRNAWSL EEETQLLQIV AELRNREDLS SDINWTLVAQ MLGTRTRLQC RYKFQQLTKA 420
ASKFELQENV WLLERIYDSL LNNGGKIHWE NIVKEANGRW TRDQMLFQFI NLKKMIPSYD 480
NLPLLEATKS AIDDFKVVLS GFSN 505
Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
Interpro

IPR009057--Homeodomain-like
IPR017930--Myb_dom
IPR001005--SANT/Myb
PROSITE

PS51294--HTH_MYB
Pfam

PF00249--Myb_DNA-binding
Gene Ontology

GO:0005730--C:nucleolus
GO:0043110--F:rDNA spacer replication fork barrier binding
GO:0043565--F:sequence-specific DNA binding
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0071946--P:cis-acting DNA replication termination
GO:0036278--P:positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation
GO:0043111--P:replication fork arrest
GO:0031582--P:replication fork arrest at rDNA repeats
GO:0006363--P:termination of RNA polymerase I transcription
GO:0006366--P:transcription from RNA polymerase II promoter