dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0039389 | ||||||||
| Uniprot Accession | Q9P371; SST2_SCHPO; | ||||||||
| Genbank Protein ID | NP_594773.1; | ||||||||
| Genbank Nucleotide ID | NM_001020200.2; | ||||||||
| Protein Name | AMSH-like protease sst2 | ||||||||
| Protein Synonyms/Alias | Suppressor of ste12 deletion protein 2; | ||||||||
| Gene Name | sst2 | ||||||||
| Gene Synonyms/Alias | SPAC19B12.10; | ||||||||
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) | ||||||||
| NCBI Taxa ID | 284812 | ||||||||
| Functional Description (View all) |
Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Plays a role in the multivesicular body (MVB) sorting pathway. Required for ubiquitin-dependent sorting of proteins into the endosome and subsequent trafficking to the vacuole. May regulate MVB sorting through deubiquitination of ubiquitinated ESCRT proteins. | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
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| Sequence (Fasta) | MNILQGSEAP LSYEEIASRA GAFDFNKNIP LKNWLRTSTT ISKQAHVYVS EHDYSNGVFL 60 LFRYCELFMK CQKHPDAAAY KKELFDYYQG VRNALEEIEL IKPIVKEQYE QYQCQKNDLD 120 DLKKLSMKDS QPSLEKPVSY VDEPILEQWA LSDLQILPPS STDLLSPDSQ KLSKSSSDLP 180 QFDYPSLNSS PTFNSNLPIS SSRFEKTSLS DSKLVSPEPL DDNKDIQFIK KPIYTRTSEP 240 RPKPAGTFKI HAYTEGGKPL RTIYLPKLLK KVFLDVVKPN TKKNLETCGI LCGKLRQNAF 300 FITHLVIPLQ EATSDTCGTT DEASLFEFQD KHNLLTLGWI HTHPTQTCFM SSVDLHTHCS 360 YQLMLPEAIA IVMAPSKNTS GIFRLLDPEG LQTIVKCRKP GLFHPHEGKV YTMVAQPGHV 420 REINSKLQVV DLRVK 436 |
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| Keyword | KW-0002--3D-structure |
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| Interpro | IPR000555--JAMM/MPN+_dom |
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| PROSITE | |||||||||
| Pfam | PF01398--JAB |
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| Gene Ontology | GO:0032153--C:cell division site |