dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0039387
Uniprot Accession Q9P305; IGO2_YEAST; D3DL81;
Genbank Protein ID NP_036194.1;
Genbank Nucleotide ID NM_001184441.1;
Protein Name mRNA stability protein IGO2
Protein Synonyms/Alias Initiation of G zero protein 2;
Gene Name IGO2
Gene Synonyms/Alias YHR132W-A;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Required for TORC1 to properly control gene expression and chronological life span. Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway.
Phosphorylation Sites
 dbPAF PTMs: 21 (View all)
PositionPeptidesSourceReferences ( PMIDs )
2------MSEDLSPTScurated19823750; 24961812; 19547744
6--MSEDLSPTSSRVDdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;SysPTM 2.0;UniProt;curated15665377; 18407956; 16381945; 23193290; 21081558; 19366988;
8MSEDLSPTSSRVDLScurated26040406; 24961812
9SEDLSPTSSRVDLSNdbPTM 3.0;curated18407956; 16381945; 23193290; 22369663; 24961812
10EDLSPTSSRVDLSNPcurated26040289; 22369663; 24961812
31GVDLSKLSPQELKLYcurated24961812
60HKMQDRQYFDSGDYAcurated19823750
63QDRQYFDSGDYALKKdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17287358; 18407956; 16381945; 23193290; 21126336; 19823750;
66QYFDSGDYALKKAGVPhosphoGRID 2.0;curated19823750; 19795423; 22817900; 25521595; 20377248
85DVIVNNSSNNLPVTNcurated25315811
99NPSGLRESIIRRRMSPhosphoPep 2.0;curated19060867; 26040289
106SIIRRRMSSSSGGDSdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;curated11875433; 17563356; 18407956; 16381945; 23193290; 21177495;
107IIRRRMSSSSGGDSIdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;curated11875433; 18407956; 16381945; 23193290; 21177495; 19779198;
108IRRRMSSSSGGDSISdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;UniProt;curated17563356; 18407956; 16381945; 23193290; 21177495; 19779198;
109RRRMSSSSGGDSISRdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;curated18407956; 16381945; 23193290; 21177495; 19684113; 19779198;
113SSSSGGDSISRQGSIPhosphoGRID 2.0;PhosphoPep 2.0;curated21177495; 19779198; 19060867; 26040289; 22369663; 22817900
115SSGGDSISRQGSISSPhosphoGRID 2.0;PhosphoPep 2.0;curated21177495; 19779198; 19060867; 26040289; 22369663; 22817900;
119DSISRQGSISSGPPPPhosphoGRID 2.0;PhosphoPep 2.0;UniProt;curated21177495; 21126336; 19779198; 19060867; 26040406; 26040289;
121ISRQGSISSGPPPRSPhosphoGRID 2.0;PhosphoPep 2.0;curated21177495; 19060867; 22817900
122SRQGSISSGPPPRSPPhosphoGRID 2.0;PhosphoPep 2.0;curated21177495; 19060867; 22369663; 22817900
Sequence
(Fasta)		MSEDLSPTSS RVDLSNPHGF TKEGVDLSKL SPQELKLYKM YGKLPSKKDL LRHKMQDRQY 60
FDSGDYALKK AGVIKSDDVI VNNSSNNLPV TNPSGLRESI IRRRMSSSSG GDSISRQGSI 120
SSGPPPRSPN K 132
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR006760--Endosulphine
PROSITE
Pfam

PF04667--Endosulfine
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0019208--F:phosphatase regulator activity
GO:0048255--P:mRNA stabilization
GO:0050790--P:regulation of catalytic activity