dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0037875
Uniprot Accession Q9HGM2; GET1_SCHPO;
Genbank Protein ID NP_596798.1;
Genbank Nucleotide ID NM_001023818.2;
Protein Name Protein get1
Protein Synonyms/Alias Guided entry of tail-anchored proteins 1;
Gene Name get1
Gene Synonyms/Alias SPBC543.10;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble get3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
65KELNATSSQDQFAKWdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
Sequence
(Fasta)
MMDLIISTIL LSLFIHFFDK FAKKRTIDGA YRIYVSVSNN KDLKKNKEIL EQLLTVKKEL 60
NATSSQDQFA KWARLNRKYE QLSQEWEKQS ANVKIFQDTF KRVLSLFLWI LTRGFRFYIQ 120
FKESKTPVFF LPAFLLPSWA LWVLSLPRSI YGSVSLTVWN FAVQKTISGI F 172
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport

Interpro

IPR027538--Get1_fungi
IPR028945--WRB/Get1

PROSITE
Pfam

PF04420--CHD5

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0005789--C:endoplasmic reticulum membrane
GO:0043529--C:GET complex
GO:0016021--C:integral component of membrane
GO:0006874--P:cellular calcium ion homeostasis
GO:0034620--P:cellular response to unfolded protein
GO:0045048--P:protein insertion into ER membrane
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER
GO:0071816--P:tail-anchored membrane protein insertion into ER membrane