dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0037861
Uniprot Accession Q9HDW7; ATC2_SCHPO; Q9UTX0;
Genbank Protein ID NP_593890.1;
Genbank Nucleotide ID NM_001019320.2;
Protein Name Calcium-transporting ATPase 2
Protein Synonyms/Alias
Gene Name pmc1
Gene Synonyms/Alias SPAPB2B4.04c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports the calcium to the vacuole and participates in the control of the cytosolic free calcium.
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
15DDSSRPPSVHSERNQcurated22817900
91YTSYVSHSDAEPEQAcurated22817900
Sequence
(Fasta)		MPTYNDDDDS SRPPSVHSER NQKPSSSQFL GVPSSNYNQR ENSSRSGSST ISREPSSSGT 60
MYPMASRDSM KESYDKNKGT PPDYTSYVSH SDAEPEQASS KSSTSIEDLL HTEYDDAPFA 120
FSIPLLQRLQ DPKNTSLLHA IHGLKGLCKG LKVDPSTGIS THEPHYADKL QMSDILNDDS 180
NPKLVVHLDR IRSQDNNPEA KVSHDSDRVK YYGKNVLPEH DSKGLIRLML EAFKDKVLIL 240
LSIAAVVSLA LGLYQTFGQP PTLDPITGKP EPRVEWVEGV AIMAAIVIVV TVGGVNDWQK 300
ELQFKKLNAK VSNFDVQVLR DGAVHSTSVF DLVVGDVLFV EAGDVVPVDG VLIESNNLVL 360
DESAMTGETD NIKKVDANTA IERTSPDVEY RKNADPYLIS GTTILEGNGK LLVTAVGVNS 420
FNGRTTMAMR TEGQATPLQL RLSRVADAIA KLGGAASALL FIVLLIEFLV RLKSNDSSSK 480
NKGQEFLQIL IVSVTLLVVA VPEGLPLAVT LALAFATNRM QKDNNLVRHL QACETMGTAT 540
NICSDKTGTL TQNRMTVVAG GFGTDVLFFD HNDETPTNVD QGSDSSKFED AGASAFAFKR 600
LSPELRDLTL YSIAVNSTCR QLFEDNSDTP RFIGSKTETA LLDMSVKELG LTNVDSMRSS 660
VDIKQFFSFS SDRKASGAIF EYKDKYYFVV KGMPERVLQQ STSVITNGSL DEVEDMHSHA 720
DYFKEMITGY AKRSLRTLGL CYRVFDSWPP KDIPTNDEDS SNPLKWEDAF TDMTFLGFFG 780
IMDPIRPDVP LAVKVCQGAG VTVRMVTGDN IVTAKAIASQ CGIYTEDGIS MEGPEFRSLS 840
DEKRLEILPK LDVLARSSPL DKQLLIEGLQ KLGNVVAVTG DGTNDAPALK KANVGFSMGK 900
SGTEVAKEAS DIILMDDNFS SIVKAIAWGR TVNDAVKKFL QFQITVNITA VFLTIISAVA 960
STDQSSVLTA VQLLWVNLIM DTLAALALAT DPPTPEVLKR KPEKPGASLF TFDMWKMIIC 1020
QSMYQLAVTL VLHFAGNSIF HYPSNTADMN TIVFNTFVWL QLFNEINNRR LDNKLNIFER 1080
INHNFLFIAI FVIVAGIQVI IVFFGGAAFS VKRIDGKGWA ISIVFGVISI PLGALIRCVP 1140
NNFLRKVLPV KTIDTVFSWI LNPRFRSKRR STDHDVESLS LIPYEPTSPN EVIDSIRHSL 1200
GFVQRIRGGR IRHLLNNSKF DKQMEALPER LRPRVKQRFM KIRSPSVSSA TSVALMIPIS 1260
TLVSEASGRL GGHDIWISHN RQALDKKSSN VH 1293
Keyword

KW-0067--ATP-binding
KW-0106--Calcium
KW-0109--Calcium transport
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0406--Ion transport
KW-0460--Magnesium
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
KW-0926--Vacuole
Interpro

IPR006068--ATPase_P-typ_cation-transptr_C
IPR004014--ATPase_P-typ_cation-transptr_N
IPR023299--ATPase_P-typ_cyto_domN
IPR018303--ATPase_P-typ_P_site
IPR023298--ATPase_P-typ_TM_dom
IPR008250--ATPase_P-typ_transduc_dom_A
IPR023214--HAD-like_dom
IPR006408--P-type_ATPase_IIB
IPR001757--P_typ_ATPase
PROSITE

PS00154--ATPASE_E1_E2
Pfam

PF00689--Cation_ATPase_C
PF00690--Cation_ATPase_N
PF00122--E1-E2_ATPase
PF00702--Hydrolase
Gene Ontology

GO:0071627--C:integral component of fungal-type vacuolar membrane
GO:0005524--F:ATP binding
GO:0005509--F:calcium ion binding
GO:0005388--F:calcium-transporting ATPase activity
GO:0070588--P:calcium ion transmembrane transport
GO:0006874--P:cellular calcium ion homeostasis