dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0034320 |
| Uniprot Accession | Q99385; VCX1_YEAST; D6VRM2; O13580; O13581; |
| Genbank Protein ID | NP_010155.1; |
| Genbank Nucleotide ID | NM_001180187.1; |
| Protein Name | Vacuolar calcium ion transporter |
| Protein Synonyms/Alias | High copy number undoes manganese protein 1;Manganese resistance 1 protein;Vacuolar Ca(2+)/H(+) exchanger; |
| Gene Name | VCX1 |
| Gene Synonyms/Alias | HUM1;MNR1;YDL128W; |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID | 559292 |
| Functional Description (View all) |
Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole. |
| Phosphorylation Sites |
dbPAF PTMs: 3 |
| Sequence (Fasta) | MDATTPLLTV ANSHPARNPK HTAWRAAVYD LQYILKASPL NFLLVFVPLG LIWGHFQLSH 60 TLTFLFNFLA IIPLAAILAN ATEELADKAG NTIGGLLNAT FGNAVELIVS IIALKKGQVR 120 IVQASMLGSL LSNLLLVLGL CFIFGGYNRV QQTFNQTAAQ TMSSLLAIAC ASLLIPAAFR 180 ATLPHGKEDH FIDGKILELS RGTSIVILIV YVLFLYFQLG SHHALFEQQE EETDEVMSTI 240 SRNPHHSLSV KSSLVILLGT TVIISFCADF LVGTIDNVVE STGLSKTFIG LIVIPIVGNA 300 AEHVTSVLVA MKDKMDLALG VAIGSSLQVA LFVTPFMVLV GWMIDVPMTL NFSTFETATL 360 FIAVFLSNYL ILDGESNWLE GVMSLAMYIL IAMAFFYYPD EKTLDSIGNS L 412 |
| Keyword | KW-0002--3D-structure |
| Interpro | IPR004713--CaH_exchang |
| PROSITE | |
| Pfam | PF01699--Na_Ca_ex |
| Gene Ontology | GO:0000324--C:fungal-type vacuole |