dbPAF Protein Information
| Tag | Content | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0034318 | ||||||||||||||||||||
| Uniprot Accession | Q99380; OST4_YEAST; D6VRC4; | ||||||||||||||||||||
| Genbank Protein ID | NP_010049.1; | ||||||||||||||||||||
| Genbank Nucleotide ID | NM_001180292.1; | ||||||||||||||||||||
| Protein Name | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST4 | ||||||||||||||||||||
| Protein Synonyms/Alias | |||||||||||||||||||||
| Gene Name | OST4 | ||||||||||||||||||||
| Gene Synonyms/Alias | YDL232W; | ||||||||||||||||||||
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) | ||||||||||||||||||||
| NCBI Taxa ID | 559292 | ||||||||||||||||||||
| Functional Description (View all) |
Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. OST4 is required for recruitment of OST3 or OST6 to the OST complex. It is essential for cell growth at 37 but not at 25 degrees Celsius. | ||||||||||||||||||||
| Phosphorylation Sites |
dbPAF PTMs: 4
|
||||||||||||||||||||
| Sequence (Fasta) | MISDEQLNSL AITFGIVMMT LIVIYHAVDS TMSPKN 37 | ||||||||||||||||||||
| Keyword | KW-0002--3D-structure |
||||||||||||||||||||
| Interpro | IPR018943--Oligosaccaryltransferase |
||||||||||||||||||||
| PROSITE | |||||||||||||||||||||
| Pfam | PF10215--Ost4 |
||||||||||||||||||||
| Gene Ontology | GO:0005789--C:endoplasmic reticulum membrane |