dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0034312
Uniprot Accession Q99332; HPH1_YEAST; D6W322;
Genbank Protein ID NP_014969.3;
Genbank Nucleotide ID NM_001183744.3;
Protein Name Protein HPH1
Protein Synonyms/Alias Functionally related to TCP1 protein 1;High pH protein 1;
Gene Name FRT1
Gene Synonyms/Alias HPH1;YOR324C;O6159;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Calcineurin-dependent protein required for growth under high NaCl, alkaline pH and cell wall stress.
Phosphorylation Sites
 dbPAF PTMs: 22 (View all)
PositionPeptidesSourceReferences ( PMIDs )
34FCKGRRASSGDAVKIcurated25315811
35CKGRRASSGDAVKIKcurated25315811
69AHFSKSSSRLPVIAVcurated20377248
86NPVVPRPSTEVNLGScurated20377248
87PVVPRPSTEVNLGSLcurated20377248
165RVGRHSRSYSGASSLcurated25315811
166VGRHSRSYSGASSLDdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
167GRHSRSYSGASSLDDPhosphoGRID 2.0;UniProt;curated19779198; 22817900; 25315811
171RSYSGASSLDDPFRVdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19779198; 19366988
228SSSQRRSSAGSFDYEdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated17563356; 18407956; 16381945; 23193290; 19684113; 19779198;
231QRRSSAGSFDYERKRdbPTM 3.0;PhosphoGRID 2.0;curated17563356; 16381945; 23193290; 19684113; 19779198; 26040289
342SEDVDRRSLNGVYPSdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19779198; 19366988; 26040289;
347RRSLNGVYPSLGYLTcurated25315811
362NQRKPRNSSGSSTAPdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
363QRKPRNSSGSSTAPGdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 25315811
365KPRNSSGSSTAPGTDcurated26040289
367RNSSGSSTAPGTDTLcurated26040289; 25315811
407NNNGSAATPDSSSNScurated25315811
410GSAATPDSSSNSISKcurated22817900; 25315811; 20377248
412AATPDSSSNSISKSNcurated22369663
Sequence
(Fasta)		MNLLIDRMEN PGSRNCTLLP PSFPRGFCKG RRASSGDAVK IKESGLQPQP QPEPLQAKTN 60
VAHFSKSSSR LPVIAVNDNP VVPRPSTEVN LGSLLQKERE KEKEEQPALH DRRHLYVTKN 120
RAHGVRQRSL EMTSLPVLGS TKTGKFSDFL FEDDIDNRVG RHSRSYSGAS SLDDPFRVSP 180
KTDFNSNRAR LSCLSKGRRG SMSVFQSCHT GLAFNQIQGS SSSQRRSSAG SFDYERKRLV 240
NQFLQPSLGN SDPFDTLRES VVFEPSSTAG GIKLGNMHSQ SQISVNSSPS TSLFYHDLDG 300
SAVNDSSSFL YSRSNVPAFL SSSAFSSTSS TSSDSEDVDR RSLNGVYPSL GYLTNQRKPR 360
NSSGSSTAPG TDTLGFKYLL NRQKSADSST RFKSVLKVNN NNGSAATPDS SSNSISKSNS 420
NLNDNIDELN YYQNHISTLL VKIENEMRRN LNDTIIKNEN NVQKTIQKYD LLSGELTLLL 480
DEMTTLRTTV INQFLVKLKS DFDEDDNKAF INELKISVEE SVAQLQGLER RMEVCQERLN 540
KQKSSLREMD SLIELKNVLN KSKNNTKSIY LYRYFIIDII AFLLMGGFIV YVKNLLTRFF 600
TR 603
Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR025752--HPH_family
PROSITE
Pfam

PF13694--Hph
Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0071469--P:cellular response to alkaline pH
GO:0071472--P:cellular response to salt stress