dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0034305
Uniprot Accession Q99312; ISN1_YEAST; D6W2L2;
Genbank Protein ID NP_014798.3;
Genbank Nucleotide ID NM_001183574.3;
Protein Name IMP-specific 5'-nucleotidase 1
Protein Synonyms/Alias
Gene Name ISN1
Gene Synonyms/Alias YOR155C;O3548;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 IMP-specific 5'-nucleotidase involved in IMP (inosine 5'-phosphate) degradation.
Phosphorylation Sites
 dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
79EFDSRNMSQDEIEDGPhosphoGRID 2.021126336
88DEIEDGASSQSLNILdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 21126336; 19366988; 22369663;
89EIEDGASSQSLNILGdbPTM 3.0;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19060867; 19366988; 25315811
91EDGASSQSLNILGQSPhosphoGRID 2.0;curated19779198; 22369663
399QQFYNPESPIQPSETdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 20377248
Sequence
(Fasta)		MSSRYRVEYH LKSHRKDEFI DWVKGLLASP FVLHAVSHEG DYNDDLATTQ RVRSQYADIF 60
KDIEGLIKDK IEFDSRNMSQ DEIEDGASSQ SLNILGQSRL NLLVPSIGTF FTELPLEQAF 120
LWEDSQRAIS ARRMVAPSFN DIRHILNTAQ IFHFKKQENL HNGKVLRLVT FDGDVTLYED 180
GGSLVYTNPV IPYILKLLRC GINVGIVTAA GYDEAGTYEN RLKGLIVALH DSTDIPVSQK 240
QNLTIMGGES SYLFRYYEDP EEDNFGFRQI DKEEWLLPRM KAWSLEDVEK TLDFAERTLN 300
RLRKRLNLPS EISIIRKVRA VGIVPGERYD EASKRQVPVK LDREQLEEIV LTLQNTLESF 360
APSRRIQFSC FDGGSDVWCD IGGKDLGVRS LQQFYNPESP IQPSETLHVG DQFAPVGSAN 420
DFKARLAGCT LWIASPQETV NYLHRLLETD 451
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0460--Magnesium
KW-0546--Nucleotide metabolism
KW-1185--Reference proteome
Interpro

IPR023214--HAD-like_dom
IPR009453--ISN1
PROSITE
Pfam

PF06437--ISN1
Gene Ontology

GO:0050483--F:IMP 5'-nucleotidase activity
GO:0000287--F:magnesium ion binding
GO:0016311--P:dephosphorylation
GO:0006190--P:inosine salvage
GO:0071590--P:nicotinamide riboside biosynthetic process
GO:0071592--P:nicotinic acid riboside biosynthetic process
GO:0009117--P:nucleotide metabolic process