dbPAF Protein Information
| Tag | Content | ||||||||||||||||||||
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| dbPAF ID | dbPAF-0034303 | ||||||||||||||||||||
| Uniprot Accession | Q99297; ODC2_YEAST; D6W2S7; O13594; | ||||||||||||||||||||
| Genbank Protein ID | NP_014865.1; | ||||||||||||||||||||
| Genbank Nucleotide ID | NM_001183641.1; | ||||||||||||||||||||
| Protein Name | Mitochondrial 2-oxodicarboxylate carrier 2 | ||||||||||||||||||||
| Protein Synonyms/Alias | |||||||||||||||||||||
| Gene Name | ODC2 | ||||||||||||||||||||
| Gene Synonyms/Alias | YOR222W;YOR50-12; | ||||||||||||||||||||
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) | ||||||||||||||||||||
| NCBI Taxa ID | 559292 | ||||||||||||||||||||
| Functional Description (View all) |
Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2-oxoglutarate, adipate, glutarate, 2-oxopimelate, oxaloacetate, citrate and malate. The main physiological role is probably to supply 2-oxoadipate and 2-oxoglutarate from the mitochondrial matrix to the cytosol where they are used in the biosynthesis of lysine and glutamate, respectively, and in lysine catabolism. | ||||||||||||||||||||
| Phosphorylation Sites |
dbPAF PTMs: 4
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| Sequence (Fasta) | MSSDSNAKPL PFIYQFISGA VAGISELTVM YPLDVVKTRF QLEVTTPTAA AVGKQVERYN 60 GVIDCLKKIV KKEGFSRLYR GISSPMLMEA PKRATKFACN DQYQKIFKNL FNTNETTQKI 120 SIAAGASAGM TEAAVIVPFE LIKIRMQDVK SSYLGPMDCL KKTIKNEGIM GLYKGIESTM 180 WRNALWNGGY FGVIYQVRNS MPVAKTKGQK TRNDLIAGAI GGTVGTMLNT PFDVVKSRIQ 240 SVDAVSSAVK KYNWCLPSLL VIYREEGFRA LYKGFVPKVC RLAPGGSLML VVFTGMMNFF 300 RDLKYGH 308 |
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| Keyword | KW-0181--Complete proteome |
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| Interpro | IPR002113--Aden_trnslctor |
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| PROSITE | PS50920--SOLCAR |
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| Pfam | PF00153--Mito_carr |
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| Gene Ontology | GO:0016021--C:integral component of membrane |