dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0034301
Uniprot Accession Q99288; DET1_YEAST; D6VS38; P87337; Q05314; Q7LHX4;
Genbank Protein ID NP_010336.3;
Genbank Nucleotide ID NM_001180359.3;
Protein Name Broad-range acid phosphatase DET1
Protein Synonyms/Alias Decreased ergosterol transport protein 1;
Gene Name DET1
Gene Synonyms/Alias YDR051C;D4202;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Metal-independent, broad-range acid phosphatase. Involved, either directly or indirectly, in the bidirectional transport of sterols between the endoplasmic reticulum and the plasma membrane.
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
248DVYDRVASFQETLFRdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19366988
Sequence
(Fasta)		MCEENVHVSE DVAGSHGSFT NARPRLIVLI RHGESESNKN KEVNGYIPNH LISLTKTGQI 60
QARQAGIDLL RVLNVDDHNL VEDLAKKYIK DESSRRTLPL KDYTRLSREK DTNIVFYTSP 120
YRRARETLKG ILDVIDEYNE LNSGVRICED MRYDPHGKQK HAFWPRGLNN TGGVYENNED 180
NICEGKPGKC YLQYRVKDEP RIREQDFGNF QKINSMQDVM KKRSTYGHFF FRFPHGESAA 240
DVYDRVASFQ ETLFRHFHDR QERRPRDVVV LVTHGIYSRV FLMKWFRWTY EEFESFTNVP 300
NGSVMVMELD ESINRYVLRT VLPKWTDCEG DLTT 335
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0378--Hydrolase
KW-0445--Lipid transport
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0813--Transport
Interpro

IPR013078--His_Pase_superF_clade-1
IPR029033--His_PPase_superfam
IPR001345--PG/BPGM_mutase_AS
PROSITE

PS00175--PG_MUTASE
Pfam

PF00300--His_Phos_1
Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0003993--F:acid phosphatase activity
GO:0016311--P:dephosphorylation
GO:0032366--P:intracellular sterol transport