dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0034300
Uniprot Accession Q99287; SEY1_YEAST; D6W2M3;
Genbank Protein ID NP_014808.1;
Genbank Nucleotide ID NM_001183584.1;
Protein Name Protein SEY1
Protein Synonyms/Alias Synthetic enhancer of YOP1 protein;
Gene Name SEY1
Gene Synonyms/Alias YOR165W;O3590;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Cooperates with the reticulon proteins RTN1 and RTN2 and the tubule-shaping DP1 family protein YOP1 to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization.
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
331PLKGNLGSLTSQLVKPhosphoGRID 2.0;curated19823750; 19795423
485DHVIHLLSHPSKKVWcurated22369663
488IHLLSHPSKKVWDDIcurated22369663
Sequence
(Fasta)
MADRPAIQLI DEEKEFHQSA LQYFQQCIGN RDVGLDYHVI SVFGSQSSGK STLLNVLFNT 60
NFDTMDAQVK RQQTTKGIWL AHTKQVNTTI EIDNDRPDIF VLDVEGSDGS ERGEDQDFER 120
KAALFAIAVS EVLIVNMWEQ QIGLYQGNNM ALLKTVFEVN LSLFGKNDND HKVLLLFVIR 180
DHVGVTPLSS LSDSVTRELE KIWTELSKPA GCEGSSLYDY FDLKFVGLAH KLLQEDKFTQ 240
DVKKLGDSFV MKGTENYYFK PQYHHRLPLD GWTMYAENCW DQIERNKDLD LPTQQILVAR 300
FKTEEISNEA LEEFISKYDE SIAPLKGNLG SLTSQLVKLK EECLTKYDEQ ASRYARNVYM 360
EKREALNTKL NSHISGTINE FLESLMEKLW DDLKLEVSSR DKATTSFVES VAAGKSKIEK 420
EFNESMETFK KLGLLISNEE ITCKFSDDIE ERIKQLRDAE LKAKIGRIKK NLVPELKDHV 480
IHLLSHPSKK VWDDIMNDFE STIKDNISAY QVEKDKYDFK IGLSESENAK IYKNIRILAW 540
RTLDTTVHDY LKIDTIVSIL RDRFEDVFRY DAEGSPRLWK TEEEIDGAFR VAKEHALEVF 600
EVLSLAVTSD NVEIIPDVPM AEEESGEDNE IYRDNEGVFH SRRFAHILTE LQKENVLDQF 660
RRQINITVLD SKRSIITTRT HIPPWIYVLL AVLGWNEFVA VIRNPLFVTL TLILGATFFV 720
IHKFGLWGPV VNVVQSAVGE TRTAIKDKLR QFVVEDHEVK ESFEMKDFSK NEQKEK 777
Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0342--GTP-binding
KW-0378--Hydrolase
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0346--Stress response
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR030386--G_GB1_RHD3_dom
IPR027417--P-loop_NTPase
IPR008803--RHD3/Sey1

PROSITE

PS51715--G_GB1_RHD3

Pfam

PF05879--RHD3

Gene Ontology

GO:0032541--C:cortical endoplasmic reticulum
GO:0005783--C:endoplasmic reticulum
GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0005525--F:GTP binding
GO:0003924--F:GTPase activity
GO:0048309--P:endoplasmic reticulum inheritance
GO:0016320--P:endoplasmic reticulum membrane fusion
GO:0007029--P:endoplasmic reticulum organization
GO:0061024--P:membrane organization