dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0034288
Uniprot Accession Q99222; AFI1_YEAST; D6W2I7; Q92274;
Genbank Protein ID NP_014772.1;
Genbank Nucleotide ID NM_001183548.1;
Protein Name ARF3-interacting protein 1
Protein Synonyms/Alias
Gene Name AFI1
Gene Synonyms/Alias YOR129C;YOR3296C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Involved in actin patch polarization. Required for maintaining a proper budding pattern in yeast cells. Required for proper polarized localization of the ADP-ribosylation factor ARF3 at the plasma membrane.
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
9LRRELNNSISNRSIEdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 25315811
125NLHHREQSDGSVTNScurated25315811
Sequence
(Fasta)
MLRRELNNSI SNRSIENESF PFERPNVSYI ISAEFDNKLG PILKHQYPKD IPGFNQFSHE 60
QRNGNTSVSM NLASLMIPSS IERNPGKQDI TVFTLYYNKF TQNYQLFPVP KDPRFSFNLH 120
HREQSDGSVT NSIYYDAENH QDAKNNRYTI VLEDDELECQ EVQNNQKAID NEPLFFINVA 180
NTVLDTTNDR GAVIKSIAIG TPLKTFFAFK NIIVLVLDLY MKAPTQAAAT DILLDCFNML 240
NSIDLTLIND IHSKSSIQEV LHSIHDESII TKVFLDPDST LKKLFCINGF DTKDKYGNIV 300
TFHDQLIQYH FTRFQPKTLP PFLLKIPLQF NMIRREPIYI ENDYNELVLK FLDKFVPYLL 360
KAGQKVNAWK LVINSTKLSK EDLCAFILSL ANITATYASD PQSYFKGNAA LIFPYMDISL 420
VDGLRAYVAS NSDFVGCFAI IGTANPIFRY QLDIWDYYYD VDEGVFYENN SPEKEKPDTV 480
AEVKIGPNPL RKIFNRPHFS TNAVNESQVN LGQKLFSLLI DEYHDSDTIM SVLRRLNVLQ 540
LENLLDALKR REIPPNIALK DEYIMFYKDF FIFPEFFDYF TLHSIELLSN LDNCLFSLGN 600
TCQLFSTEQI YSQLSQILDI VKELFRMVSV SRTNIEKFLN ACLNYSPFKI LPTAQLHGDN 660
ISRWSFESEV RQGFDNFNSY MGIEKDPHGV IVSAIDLFTQ IYSFDILAFF LTFITKESGQ 720
DLPFTKSLSR RRTYLTRIAQ SSSLRQFLQL STRPNIRILG GNGQGTGNSN YPEFTNASSV 780
ISPKLRASPL LERRASKICY AITKLLYRLE CHPIGMALLK KYLHNQLREA YLESKRHFIS 840
KKGDSTNTSS TIASSSFAGA SVPLSSNESG MLNGLKQINE QQESTLETTQ KED 894
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1185--Reference proteome

Interpro

IPR012860--Afi1_N

PROSITE
Pfam

PF07792--Afi1

Gene Ontology

GO:0005938--C:cell cortex
GO:0005935--C:cellular bud neck
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0051666--P:actin cortical patch localization
GO:0008105--P:asymmetric protein localization
GO:0000282--P:cellular bud site selection