dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0034287
Uniprot Accession Q99220; OS9_YEAST; D6VS43; Q04313;
Genbank Protein ID NP_010342.3;
Genbank Nucleotide ID NM_001180365.3;
Protein Name Protein OS-9 homolog
Protein Synonyms/Alias
Gene Name YOS9
Gene Synonyms/Alias YDR057W;D4222;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation. The recognition of targets is N-glycan specific.
Phosphorylation Sites
 dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
35DPIVSNKYLISYIDEPhosphoGRID 2.0;curated21177495; 22817900
46YIDEDDWSDRILQNQPhosphoGRID 2.0;curated21177495; 22817900
505ARMDDDESTSHTTRDPhosphoGRID 2.0;curated21177495; 22817900
506RMDDDESTSHTTRDIcurated22817900
507MDDDESTSHTTRDIGPhosphoGRID 2.0;curated21177495; 22817900
509DDESTSHTTRDIGEAPhosphoGRID 2.0;curated21177495; 22817900
510DESTSHTTRDIGEAGPhosphoGRID 2.0;curated21177495; 22817900
Sequence
(Fasta)		MQAKIIYALS AISALIPLGS SLLAPIEDPI VSNKYLISYI DEDDWSDRIL QNQSVMNSGY 60
IVNMGDDLEC FIQNASTQLN DVLEDSNEHS NSEKTALLTK TLNQGVKTIF DKLNERCIFY 120
QAGFWIYEYC PGIEFVQFHG RVNTKTGEIV NRDESLVYRL GKPKANVEER EFELLYDDVG 180
YYISEIIGSG DICDVTGAER MVEIQYVCGG SNSGPSTIQW VRETKICVYE AQVTIPELCN 240
LELLAKNEDQ KNASPILCRM PAKSKIGSNS IDLITKYEPI FLGSGIYFLR PFNTDERDKL 300
MVTDNAMSNW DEITETYYQK FGNAINKMLS LRLVSLPNGH ILQPGDSCVW LAEVVDMKDR 360
FQTTLSLNIL NSQRAEIFFN KTFTFNEDNG NFLSYKIGDH GESTELGQIT HSNKADINTA 420
EIRSDEYLIN TDNELFLRIS KEIAEVKELL NEIVSPHEME VIFENMRNQP NNDFELALMN 480
KLKSSLNDDN KVEQINNARM DDDESTSHTT RDIGEAGSQT TGNTESEVTN VAAGVFIEHD 540
EL 543
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0256--Endoplasmic reticulum
KW-0325--Glycoprotein
KW-0430--Lectin
KW-0472--Membrane
KW-1185--Reference proteome
KW-0732--Signal
Interpro

IPR012913--PRKCSH
PROSITE

PS00014--ER_TARGET
Pfam

PF07915--PRKCSH
Gene Ontology

GO:0005788--C:endoplasmic reticulum lumen
GO:0005789--C:endoplasmic reticulum membrane
GO:0034099--C:luminal surveillance complex
GO:0070492--F:oligosaccharide binding
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0030433--P:ER-associated ubiquitin-dependent protein catabolic process
GO:0030970--P:retrograde protein transport, ER to cytosol