dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0034286
Uniprot Accession Q99216; PNO1_YEAST; D6W2K3; Q02462; Q7LHP7;
Genbank Protein ID NP_014788.1;
Genbank Nucleotide ID NM_001183564.1;
Protein Name Pre-rRNA-processing protein PNO1
Protein Synonyms/Alias Partner of NOB1;Ribosomal RNA-processing protein 20;
Gene Name PNO1
Gene Synonyms/Alias DIM2;RRP20;YOR145C;O3513;YOR3513C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species. Recruits DIM1 to nucleolar pre-RNAs. Indirectly required for cleavage at the A2 site of the 20S pre-rRNA, forming 18S rRNA, and at A1 and A2 sites of other pre-rRNAs.
Phosphorylation Sites
 dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
11PTALKKATVTPVSGQPhosphoGRID 2.021126336
13ALKKATVTPVSGQDGcurated25315811
16KATVTPVSGQDGGSScurated25315811
22VSGQDGGSSRIIGINcurated25315811
33IGINNTESIDEDDDDPhosphoGRID 2.019779198
47DDVLLDDSDNNTAKEPhosphoGRID 2.0;UniProt;curated19779198; 26040289; 22817900; 19823750
51LDDSDNNTAKEEVEGPhosphoGRID 2.0;UniProt;curated19779198; 26040406; 22817900; 19823750
246HIRMARESVVSLILGcurated22817900
Sequence
(Fasta)		MVAPTALKKA TVTPVSGQDG GSSRIIGINN TESIDEDDDD DVLLDDSDNN TAKEEVEGEE 60
GSRKTHESKT VVVDDQGKPR FTSASKTQGN KIKFESRKIM VPPHRMTPLR NSWTKIYPPL 120
VEHLKLQVRM NLKTKSVELR TNPKFTTDPG ALQKGADFIK AFTLGFDLDD SIALLRLDDL 180
YIETFEVKDV KTLTGDHLSR AIGRIAGKDG KTKFAIENAT RTRIVLADSK IHILGGFTHI 240
RMARESVVSL ILGSPPGKVY GNLRTVASRL KERY 275
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0690--Ribosome biogenesis
KW-0694--RNA-binding
Interpro

IPR004087--KH_dom
IPR004088--KH_dom_type_1
PROSITE
Pfam
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0003723--F:RNA binding
GO:0051082--F:unfolded protein binding
GO:0000447--P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5
8S rRNA an-- LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5
8S rRNA, L--U-rRNA)
GO:0000472--P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5
8S rRNA, L--U-rRNA)
GO:0006461--P:protein complex assembly