dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0032541
Uniprot Accession Q92398; SPM1_SCHPO;
Genbank Protein ID NP_595289.1;
Genbank Nucleotide ID NM_001021196.2;
Protein Name Mitogen-activated protein kinase spm1
Protein Synonyms/Alias
Gene Name spm1
Gene Synonyms/Alias pmk1;SPBC119.08;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Regulates cell integrity and functions coordinately with the protein kinase C pathway (pck1 and pck2). Involved the regulation of wall architecture, cell shape, cytokinesis in exponential and stationary phase, and metabolism of ions.
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
186EENPGFMTEYVATRWdbPTM 3.0;UniProt18257517; 16381945; 23193290
188NPGFMTEYVATRWYRdbPTM 3.0;SysPTM 2.0;UniProt18257517; 16381945; 23193290; 19366988
Sequence
(Fasta)
MDRRHRVYRV FNQEMYVEPN FKVVKELGQG AYGIVCAARN VASKDQEAVA IKKITNVFSK 60
SILTKRALRE IKLLIHFRNH RNITCIYDLD IINPYNFNEV YIYEELMEAD LNAIIKSGQP 120
LTDAHFQSFI YQILCGLKYI HSANVIHRDL KPGNLLVNAD CELKICDFGL ARGCSENPEE 180
NPGFMTEYVA TRWYRAPEIM LSFSSYHKGI DVWSVGCILA ELLGGTPLFK GKDFVHQLNL 240
ILHQLGTPDE ETLSHISSSR AQEYVRSLPK QRPIPFETNF PKANPLALDL LAKLLAFDPN 300
RRISVDDALE HPYLAVWHDP SDEPVCDSVF DFSFEYIEDA NELRRVILDE VLNFRQKVRR 360
RSHPTNPTVN IPQPAQTVPS NDNGSFNVSS SSSSQTSNKK RHDHSYNETA AIDHKSDDNR 420
HN 423
Keyword

KW-0067--ATP-binding
KW-0131--Cell cycle
KW-0133--Cell shape
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR011009--Kinase-like_dom
IPR003527--MAP_kinase_CS
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS01351--MAPK
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

Gene Ontology

GO:0032153--C:cell division site
GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0044732--C:mitotic spindle pole body
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004707--F:MAP kinase activity
GO:0038067--F:MAP kinase activity involved in cell wall organization or biogenesis
GO:0004672--F:protein kinase activity
GO:0007049--P:cell cycle
GO:0000165--P:MAPK cascade
GO:0000196--P:MAPK cascade involved in cell wall organization or biogenesis
GO:0018107--P:peptidyl-threonine phosphorylation
GO:0010524--P:positive regulation of calcium ion transport into cytosol
GO:1901196--P:positive regulation of calcium-mediated signaling involved in cellular response to salt stress
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0008360--P:regulation of cell shape