dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0025228 | ||||||||
| Uniprot Accession | Q76PD2; HEL2_SCHPO; | ||||||||
| Genbank Protein ID | NP_588346.2; | ||||||||
| Genbank Nucleotide ID | NM_001023337.2; | ||||||||
| Protein Name | E3 ubiquitin-protein ligase hel2 | ||||||||
| Protein Synonyms/Alias | Histone E3 ligase 2; | ||||||||
| Gene Name | SPCC1223.01 | ||||||||
| Gene Synonyms/Alias | SPCC285.18; | ||||||||
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) | ||||||||
| NCBI Taxa ID | 284812 | ||||||||
| Functional Description (View all) |
Probable ubiquitin-protein ligase involved in the degradation-related ubiquitination of histones. Contributes to the post-translational regulation of histone protein levels by polyubiquitination of excess histones for subsequent degradation. | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
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| Sequence (Fasta) | MSPSGPNLNN KEHNRASEKK NSRTHNKKTN RNQSKEKPVS SRSVETPKNA VCLEPVGTDP 60 VSNVATVDAS KEEQDEDEQI CFICAEGITY SCVLPCNHRM CHVCALRLRA LYKTKECTFC 120 KTEWDTVLIT KDHEIDIHDV DLAKLPFQDE KLGIVYSDEH AQEESNLLLQ FNCPEDACDI 180 TCKGWFDLKL HAKVKHHKFF CDLCVKNKKV FTHEHTLFSK KGLTKHNEVG DQGSDLEITG 240 FKGHPKCEFC NTHFYDDDEL FKHCREKHER CYICDQVAGR PTHQYFKNYD SLERHFEKDH 300 YICRERECLE RKFVVFGTEI DLKAHQLDEH PHNFTQRELR EARRIIPQFS YDPPGASGRN 360 RRERTSSTPS EQSTSVNETA NSLSNLHLSR GEIAHLRQEE YVREQQARHR DFGFTLSNPA 420 PTSARPATST RTISRGKTRT LRNEDFPSLA EVANQNSSSA PSVPVSAPRL SGKSASRNHV 480 PSPPKGTKSP MASSEQAQHQ QVIDRMQKLT NYDDHKINDF KFAVSSFRGN VMPAREAVAR 540 ITKLVAKPHE QLSGVFNQIA NLLENKEKSR ELLEAWQEWK ILNAKDDTRI GTTNSNLLRL 600 KRSNRTAAQT ASVWNRIERA AAHDGPSLSA PSSSINLANI TSRPTNSSAA NTPSWGVRKA 660 RASALNARSE EDFPALPPST SKRISVQLGK KQARPVDSWG STPNTSSNRN SNTMGVSKKK 720 NGKKQTVLFH IG 733 |
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| Keyword | KW-0181--Complete proteome |
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| Interpro | IPR007087--Znf_C2H2 |
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| PROSITE | PS00518--ZF_RING_1 |
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| Pfam | |||||||||
| Gene Ontology | GO:0005737--C:cytoplasm |