dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0024465
Uniprot Accession Q6Q547; NOP10_YEAST; D3DL22;
Genbank Protein ID NP_058135.1;
Genbank Nucleotide ID NM_001184438.1;
Protein Name H/ACA ribonucleoprotein complex subunit 3
Protein Synonyms/Alias Nucleolar protein 10;Nucleolar protein family A member 3;snoRNP protein NOP10;
Gene Name NOP10
Gene Synonyms/Alias YHR072W-A;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. Essential for growth.
Phosphorylation Sites
dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
21IYTLKKVTESGEITKPhosphoPep 2.019060867
23TLKKVTESGEITKSAPhosphoPep 2.019060867
27VTESGEITKSAHPARPhosphoPep 2.019060867
36SAHPARFSPDDKYSRdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated17287358; 16381945; 23193290; 19779198; 19366988; 26040289;
Sequence
(Fasta)
MHLMYTLGPD GKRIYTLKKV TESGEITKSA HPARFSPDDK YSRQRVTLKK RFGLVPGQ 59
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0687--Ribonucleoprotein
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing

Interpro

IPR007264--H/ACA_rnp_Nop10

PROSITE
Pfam

PF04135--Nop10p

Gene Ontology

GO:0031429--C:box H/ACA snoRNP complex
GO:0005732--C:small nucleolar ribonucleoprotein complex
GO:0003723--F:RNA binding
GO:0030515--F:snoRNA binding
GO:0000469--P:cleavage involved in rRNA processing
GO:0031118--P:rRNA pseudouridine synthesis
GO:0031120--P:snRNA pseudouridine synthesis