dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0019795
Uniprot Accession Q42598; THRC_SCHPO; P78841;
Genbank Protein ID NP_594579.1;
Genbank Nucleotide ID NM_001020008.2;
Protein Name Threonine synthase
Protein Synonyms/Alias
Gene Name thrc
Gene Synonyms/Alias SPAC9E9.06c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
319KADSTQVSPSGPISAdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
321DSTQVSPSGPISAKEdbPTM 3.0;UniProt18257517; 16381945; 23193290
Sequence
(Fasta)
MSSQVSYLST RGGSSNFSFE EAVLKGLAND GGLFIPSEIP QLPSGWIEAW KDKSFPEIAF 60
EVMSLYIPRS EISADELKKL VDRSYSTFRH PETTPLKSLK NGLNVLELFH GPTFAFKDVA 120
LQFLGNLFEF FLTRKNGNKP EDERDHLTVV GATSGDTGSA AIYGLRGKKD VSVFILFPNG 180
RVSPIQEAQM TTVTDPNVHC ITVNGVFDDC QDLVKQIFGD VEFNKKHHIG AVNSINWARI 240
LSQITYYLYS YLSVYKQGKA DDVRFIVPTG NFGDILAGYY AKRMGLPTKQ LVIATNENDI 300
LNRFFKTGRY EKADSTQVSP SGPISAKETY SPAMDILVSS NFERYLWYLA LATEAPNHTP 360
AEASEILSRW MNEFKRDGTV TVRPEVLEAA RRDFVSERVS NDETIDAIKK IYESDHYIID 420
PHTAVGVETG LRCLEKTKDQ DITYICLSTA HPAKFDKAVN LALSSYSDYN FNTQVLPIEF 480
DGLLDEERTC IFSGKPNIDI LKQIIEVTLS REKA 515
Keyword

KW-0028--Amino-acid biosynthesis
KW-0181--Complete proteome
KW-0456--Lyase
KW-0597--Phosphoprotein
KW-0663--Pyridoxal phosphate
KW-1185--Reference proteome
KW-0791--Threonine biosynthesis

Interpro

IPR000634--Ser/Thr_deHydtase_PyrdxlP-BS
IPR029144--Thr_synth_N
IPR004450--Thr_synthase-like
IPR001926--TrpB-like_PLP-dep

PROSITE

PS00165--DEHYDRATASE_SER_THR

Pfam

PF00291--PALP
PF14821--Thr_synth_N

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0030170--F:pyridoxal phosphate binding
GO:0004795--F:threonine synthase activity
GO:0009088--P:threonine biosynthetic process