dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016739
Uniprot Accession Q12753; HAA1_YEAST; D6W419;
Genbank Protein ID NP_015333.1;
Genbank Nucleotide ID NM_001184105.1;
Protein Name Transcriptional activator HAA1
Protein Synonyms/Alias
Gene Name HAA1
Gene Synonyms/Alias YPR008W;LPZ8W;YP9531.01;YP9723.08;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Regulates the transcription of a set of genes, many of which encode membrane proteins. Among the genes regulated are YGR138C and YRO2. Does not seem to be dependent on copper.
Phosphorylation Sites
 dbPAF PTMs: 37 (View all)
PositionPeptidesSourceReferences ( PMIDs )
92EKQRKQCTCGTDEVCPhosphoGRID 2.019779198
111QKRHLRKSPSSSQKKcurated25315811
125KGRSISRSQPMFERVdbPTM 3.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19366988; 25315811
134PMFERVLSSTSLDSNdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
137ERVLSSTSLDSNMLSdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
231SNHQHSKSGNNWQDSPhosphoGRID 2.0;PhosphoPep 2.0;UniProt;curated21177495; 19779198; 19060867; 26040289; 22369663; 22817900;
238SGNNWQDSSVSLPAKPhosphoGRID 2.0;curated19823750; 19779198; 19795423; 22369663; 22817900; 24961812;
239GNNWQDSSVSLPAKAcurated25315811
241NWQDSSVSLPAKADSdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 15665377; 19779198; 19060867;
248SLPAKADSRLNMMDKdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19823750; 19795423; 19366988;
258NMMDKNNSVGLDLLGPHOSIDA;curated21081558; 22369663; 22817900; 19795423; 24961812; 25315811
271LGHSKRISPISNSRVdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 21177495; 20702584; 19684113;
274SKRISPISNSRVGEVPhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;curated21177495; 19684113; 19779198; 21081558; 19060867; 26040289;
276RISPISNSRVGEVSVcurated22369663
282NSRVGEVSVPLEEYIcurated24961812; 20377248
291PLEEYIPSDIDGVGRUniProt;curated19779198; 22817900
320ESIERNFSTTATAATcurated22369663; 25315811
327STTATAATGESKFDIcurated22369663
330ATAATGESKFDINDNcurated22369663; 22817900
349NSKSYSKTNSMNGNGcurated22369663; 25315811
Sequence
(Fasta)		MVLINGIKYA CERCIRGHRV TTCNHTDQPL MMIKPKGRPS TTCDYCKQLR KNKNANPEGV 60
CTCGRLEKKK LAQKAKEEAR AKAKEKQRKQ CTCGTDEVCK YHAQKRHLRK SPSSSQKKGR 120
SISRSQPMFE RVLSSTSLDS NMLSGHGALS DTSSILTSTF LDSEPGVGKI SKDYHHVPSL 180
ASISSLQSSQ SLDQNFSIPQ SPPLSSMSFN FLTGNINETN QNHSNHQHSK SGNNWQDSSV 240
SLPAKADSRL NMMDKNNSVG LDLLGHSKRI SPISNSRVGE VSVPLEEYIP SDIDGVGRVT 300
DKSSLVYDWP FDESIERNFS TTATAATGES KFDINDNCNR INSKSYSKTN SMNGNGMNNS 360
NNNNINSNGN DKNNNNSSRQ EHQGNGLFDM FTDSSSISTL SRANLLLQEK IGSQENSVKQ 420
ENYSKNPQLR HQLTSRSRSF IHHPANEYLK NTFGNSHSND IGKGVEVLSL TPSFMDIPEK 480
ERETERSPSS NYITDRPFTR KPRSSSIDVN HRYPPMAPTT VATSPGALNN AVASNLDDQL 540
SLTSLNSQPS SIANMMMDPS NLAEQSSIHS VPQSINSPRM PKTGSRQDKN IHTKKEERNP 600
LNNIHDLSQL ENVPDEMNQM FSPPLKSMNR PDAIRENSSS SNFIIQGNSM ISTPSGRNDL 660
PDTSPMSSIQ TASPPSQLLT DQGFADLDNF MSSL 695
Keyword

KW-0010--Activator
KW-0181--Complete proteome
KW-0186--Copper
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
Interpro

IPR001083--Cu_fist_DNA-bd_dom
PROSITE

PS01119--COPPER_FIST_1
PS50073--COPPER_FIST_2
Pfam

PF00649--Copper-fist
Gene Ontology

GO:0005634--C:nucleus
GO:0005507--F:copper ion binding
GO:0003677--F:DNA binding
GO:0000981--F:RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0061402--P:positive regulation of transcription from RNA polymerase II promoter in response to acidic pH
GO:0036003--P:positive regulation of transcription from RNA polymerase II promoter in response to stress
GO:0006351--P:transcription, DNA-templated