dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0016738 |
| Uniprot Accession | Q12748; CTF3_YEAST; D6VZ16; Q7LHY6; |
| Genbank Protein ID | NP_013485.1; |
| Genbank Nucleotide ID | NM_001182270.1; |
| Protein Name | Central kinetochore subunit CTF3 |
| Protein Synonyms/Alias | Chromosome loss protein 3;Chromosome transmission fidelity protein 3; |
| Gene Name | CTF3 |
| Gene Synonyms/Alias | CHL3;YLR381W; |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID | 559292 |
| Functional Description (View all) |
Component of the central kinetochore, which mediates the attachment of the centromere to the mitotic spindle by forming essential interactions between the microtubule-associated outer kinetochore proteins and the centromere-associated inner kinetochore proteins. Required for establishing bipolar spindle-microtubule attachments and proper chromosome segregation. |
| Phosphorylation Sites |
dbPAF PTMs: 6 |
| Sequence (Fasta) | MSLILDDIIL SLTNANERTP PQALKTTLSL LYEKSKQYGL SSPQLQALVR LLCETSIIDT 60 VTKVYIVENC FLPDGYLTKE LLLEIINHLG TPTVFSRYRI QTPPVLQSAL CKWLVHVYFL 120 FPVHSEREHN ISSSIWLHLW QFSFLQKWIT PLVIWQATTP VDVKPWKLSI IKRCAMHPGY 180 RDAPGSATLI LQRFQCLVGA SSQITESIIT INCNRKTLKS HRNLKLDAHF LSILKRILSR 240 AHPANFPADT VQNTIDMYLS EIHQLGADSI YPLRLQSLPE YVPSDSTVSL WDVTSLEQLA 300 QNWPQLHIPN DVDYMMKPSL NSNVLLPRKV MSRDSLKHLY SSIILIKNSR DESSSPYEWC 360 IWQLKRCFAH QIETPQEVIP IIISVSSMDN KLSSRIIQTF CNLKYLKLDE LTLKKVCGGI 420 LPLWKPELIS GTREFFVKFM ASIFMWSTRD GHDNNCTFSE TCFYVLQMIT NWVLDDKLIA 480 LGLTLLHDMQ SLLTLDKIFN NATSNRFSTM AFISSLDILT QLSKQTKSDY AIQYLIVGPD 540 IMNKVFSSDD PLLLSAACRY LVATKNKLMQ YPSTNKFVRM QNQYIMDLTN YLYRNKVLSS 600 KSLFGVSPDF FKQILENLYI PTADFKNAKF FTITGIPALS YICIIILRRL ETAENTKIKF 660 TSGIINEETF NNFFRVHHDE IGQHGWIKGV NNIHDLRVKI LMHLSNTANP YRDIAAFLFT 720 YLKSLSKYSV QNS 734 |
| Keyword | KW-0007--Acetylation |
| Interpro | |
| PROSITE | |
| Pfam | |
| Gene Ontology | GO:0000778--C:condensed nuclear chromosome kinetochore |