dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0016737 | ||||||||
| Uniprot Accession | Q12746; PGA3_YEAST; D6W0G0; | ||||||||
| Genbank Protein ID | NP_013581.1; | ||||||||
| Genbank Nucleotide ID | NM_001182488.1; | ||||||||
| Protein Name | Plasma membrane-associated coenzyme Q6 reductase PGA3 | ||||||||
| Protein Synonyms/Alias | Processing of GAS1 and ALP protein 3; | ||||||||
| Gene Name | PGA3 | ||||||||
| Gene Synonyms/Alias | NQR1;YML125C;YM4987.10C;YM7056.01C; | ||||||||
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) | ||||||||
| NCBI Taxa ID | 559292 | ||||||||
| Functional Description (View all) |
NADH-dependent cytochrome b5 reductase that reduces coenzyme Q6 at the plasma membrane and mediates lifespan extension by calorie restriction by shifting fermentative to respiratory metabolism, probably through modulating the NAD(+)/NADH ratio. | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
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| Sequence (Fasta) | MSKEDIEGTN ILDEPVHGIY IPAALFVVGV AITTYMSGEL KILWSLPILF MIIFVRAYSA 60 YKRRRSLYPD RWTSLELEDQ TIISKNTALY RFKLKTRLES LDIPAGHHVA VRVPIDGKQE 120 VRYYNPISSK LESGYLDLVV KAYVDGKVSK YFAGLNSGDT VDFKGPIGTL NYEPNSSKHL 180 GIVAGGSGIT PVLQILNEII TVPEDLTKVS LLYANETEND ILLKDELDEM AEKYPHFQVH 240 YVVHYPSDRW TGDVGYITKD QMNRYLPEYS EDNRLLICGP DGMNNLALQY AKELGWKVNS 300 TRSSGDDQVF VF 313 |
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| Keyword | KW-1003--Cell membrane |
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| Interpro | IPR017927--Fd_Rdtase_FAD-bd |
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| PROSITE | PS51384--FAD_FR |
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| Pfam | |||||||||
| Gene Ontology | GO:0005789--C:endoplasmic reticulum membrane |