dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016735
Uniprot Accession Q12734; CSR2_YEAST; D6W440;
Genbank Protein ID NP_015355.1;
Genbank Nucleotide ID NM_001184127.1;
Protein Name Transcription factor CSR2
Protein Synonyms/Alias CHS5 SPA2 rescue protein 2;
Gene Name CSR2
Gene Synonyms/Alias MRG19;YPR030W;YP9367.10;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Transcription factor involved in the regulation of fermentation and aerobic oxidation. Acts as a repressor of CYC1, which is involved in electron flow through the mitochondria under aerobic condition. Required for pseudohyphal formation upon nitrogen starvation. May be involved in viability at stationary phase and aging.
Phosphorylation Sites
 dbPAF PTMs: 25 (View all)
PositionPeptidesSourceReferences ( PMIDs )
23RDVVQNVSAGDEGDIPhosphoGRID 2.0;UniProt;curated19779198; 22817900
42ARNREMISTSLSPQKcurated22817900
43RNREMISTSLSPQKSPhosphoGRID 2.019779198
44NREMISTSLSPQKSSPhosphoGRID 2.0;curated19779198; 22817900
46EMISTSLSPQKSSGFPhosphoGRID 2.0;UniProt;curated19779198; 22817900
60FSGRRRSSSVRDALSPhosphoGRID 2.0;curated19779198; 22817900
61SGRRRSSSVRDALSSPhosphoGRID 2.0;curated19779198; 22817900
75SFFGTGNSPTSSMDDPhosphoGRID 2.020489023
103TAMCRGNSFPSDVGTPhosphoGRID 2.0;curated19779198; 22369663; 22817900; 25315811
127QPDRHRNSVPYTTIDPhosphoGRID 2.0;UniProt;curated20489023; 19779198; 22817900
130RHRNSVPYTTIDQLHPhosphoGRID 2.0;curated19779198; 22817900
142QLHTRQDTGLRRESDcurated26040406
148DTGLRRESDPVAAKQPhosphoGRID 2.0;curated20489023; 25315811
158VAAKQISSNNDIVRScurated22369663; 25315811
327NPMNNNNSPARNRHPUniProt;curated19779198; 22817900; 25315811
514TKLKDEHTQLVASRPcurated19823750
523LVASRPRSSSISSPQcurated19823750; 25315811
525ASRPRSSSISSPQKLcurated25315811
527RPRSSSISSPQKLRScurated19823750
528PRSSSISSPQKLRSYcurated19823750; 25315811
Sequence
(Fasta)		MQSTVPIAIA SNGNKRDVVQ NVSAGDEGDI LQRLARNREM ISTSLSPQKS SGFSGRRRSS 60
SVRDALSSFF GTGNSPTSSM DDYSNLMNRN YSTASTAMCR GNSFPSDVGT KAYNITGSYQ 120
PDRHRNSVPY TTIDQLHTRQ DTGLRRESDP VAAKQISSNN DIVRSFITHH ASNSTMFINR 180
VLSDYLADRG FIKQTPLYNK KSVLEISIAT SAESVFLPTT KSDETEYLSL IHGSLNQART 240
QPVGSTNTAE SDFLPSCPTM DTLNENNDLS LFPLHTQRTS PSNTARTGNA MDTSNSDRAS 300
PASNNNTTDA DSFVASGNNN PMNNNNSPAR NRHPNSHSRS LPNAWNSQMP SFSFALIFSL 360
NKSTTLSDIK VELTSNVRVV WFNGLPPTKN VNEECYNIGS LDWTLNADNF NLFIPQGAKS 420
PLDIVENHSN NRKLKVLQKL SMRKRRSFSN KAVLRENILN NLNASNSTNK LNAGVYVFTI 480
PIVLASRIPE SLYYPSARVS YSLRLATKLK DEHTQLVASR PRSSSISSPQ KLRSYSCSDS 540
YEYSQIDDTI EGETYNNDKN STGKIAFPSS WLKSAKGRLK RNNSNGRSDN NGASSSGLAM 600
QHDSEDTINL QYPLNLVRTP PEISVTTANK PLYINKVWEN CLSYEISFAQ KYVPLNGEIP 660
ITIKVAPLVK SLSVKRIRVS CREKISYRSK DYQYDFDQLD PLASDPCNPY HMRYLVRKKK 720
DRSLPLFEVA SKCTSGPSIR EEVVTNTVDD NLLAYTSSKE NNKDIPFSES FTVKTKLKFP 780
KYCEVDATKA ASLPPYGIDL FDPIKDPTQS ENTSNNGNVL GFLVGRPNRA SKTVHKIPQD 840
KNHNEVNDTN GNSNTSLQTS SNVPIQHYTR LNKPRRGLYL DSMHFKNIQC SHKLEIVLRV 900
SKTDSGSSKI IRHYEVIVDT PIYLISDLCN TSNIDLPTYD MATTESSKVL PPTFEEATSV 960
SASPRSSVSY YPDDISMQQL NLSRSTSLAN GYLSTLHPKT TAVSDSSNGA PIRDQQEQQA 1020
RPLRTEDYAL QMGNENNAYS NMDGLLSQDI FEQETAATLF KRDIVTMNFN NNIFTPRYSP 1080
RTFTNTDYNY NDNDNNDNDT EGPGPIIHPG PEPPRYDEIS S 1122
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1017--Isopeptide bond
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0832--Ubl conjugation
Interpro

IPR011022--Arrestin_C-like
PROSITE
Pfam

PF02752--Arrestin_C
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0031625--F:ubiquitin protein ligase binding
GO:0031505--P:fungal-type cell wall organization
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0006351--P:transcription, DNA-templated
GO:0070086--P:ubiquitin-dependent endocytosis