dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0016732
Uniprot Accession Q12697; YPK9_YEAST; D6W2Y9;
Genbank Protein ID NP_014934.1;
Genbank Nucleotide ID NM_001183710.1;
Protein Name Vacuolar cation-transporting ATPase YPK9
Protein Synonyms/Alias PARK9 homolog;
Gene Name YPK9
Gene Synonyms/Alias YOR291W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Vacuolar transporter which plays a role in sequestration of divalent heavy metal ions.
Phosphorylation Sites
dbPAF PTMs: 25 (View all)
PositionPeptidesSourceReferences ( PMIDs )
95EQRGRRLTESEPLVLdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 16381945; 23193290; 19779198; 19060867; 19366988;
97RGRRLTESEPLVLSSPhosphoPep 2.019060867
103ESEPLVLSSAEQSRScurated22369663
104SEPLVLSSAEQSRSScurated22369663; 25315811
108VLSSAEQSRSSSRNPUniProt;curated19779198; 26040289; 22817900
112AEQSRSSSRNPSHFRcurated25704821
116RSSSRNPSHFRFFTQcurated25704821
156AYEQDRIYGTGLSSRcurated22817900
161RIYGTGLSSRRSSIRPhosphoGRID 2.0;curated19779198; 26040289; 25704821; 22817900
162IYGTGLSSRRSSIRSPhosphoGRID 2.0;curated19779198; 22817900
165TGLSSRRSSIRSFSRcurated26040289
166GLSSRRSSIRSFSRAcurated26040289
174IRSFSRASSLSNAKScurated22369663
175RSFSRASSLSNAKSYcurated22369663; 25315811
184SNAKSYGSFSKRGRScurated22369663; 26040289
186AKSYGSFSKRGRSGScurated22369663
211DTGFVYHSATHSSSScurated26040289; 22817900
215VYHSATHSSSSLSRYcurated22817900
216YHSATHSSSSLSRYTPhosphoGRID 2.0;curated19779198; 26040289
217HSATHSSSSLSRYTTdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated17330950; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)
MDIPSSNQIQ HGQRSERNRR MPRASFSSTA TTSTAATLTS AMVLDQNNSE PYAGATFEAV 60
PSSIVSFHHP HSFQSSNLPS PHSSGNLEQR GRRLTESEPL VLSSAEQSRS SSRNPSHFRF 120
FTQEQISNAE GASTLENTDY DMAWDATPAY EQDRIYGTGL SSRRSSIRSF SRASSLSNAK 180
SYGSFSKRGR SGSRAPQRLG ENSDTGFVYH SATHSSSSLS RYTTRERIPI ELESQTDEIL 240
EDESSTHSLE SSDSRRSASE NNRGSFSGHD DVHNQHSEYL KPDYHEKFYP QYAPNLHYQR 300
FYIAEEDLVI GIAAYQTSKF WYIIYNLCCF LTFGLVYLLT RWLPHLKVKL YGVKVPLAKA 360
EWVVIENEFG EFVIQPIDRQ WYNRPLSTVL PFENYPNPSY EPNDINLSHH HANEINPNVP 420
ILITFEYRYI KFIYSPLDDL FKTNNNWIDP DWVDLSTVSN GLTKGVQEDR ELAFGKNQIN 480
LRMKTTSEIL FNEVLHPFYV FQVFSIILWG IDEYYYYAAC IFLISVLSIF DSLNEQKKVS 540
RNLAEMSHFH CDVRVLRDKF WTTISSSELV PGDIYEVSDP NITILPCDSI LLSSDCIVNE 600
SMLTGESVPV SKFPATEETM YQLCDDFQST QISSFVSKSF LYNGTNIIRA RIAPGQTAAL 660
AMVVRTGFST TKGSLVRSMV FPKPTGFKFY RDSFKYIGFM SLIAIFGFCV SCVQFIKLGL 720
DKKTMILRAL DIITIVVPPA LPATLTIGTN FALSRLKEKG IFCISPTRLN ISGKIDVMCF 780
DKTGTLTEDG LDVLGVQISE PNGVRGQKFG ELLSDIRQVF PKFSLNDCSS PLDFKSRNFF 840
MSLLTCHSLR SVDGNLLGDP LDFKMFQFTG WSFEEDFQKR AFHSLYEGRH EDDVFPENSE 900
IIPAVVHPDS NNRENTFTDN DPHNFLGVVR SFEFLSELRR MSVIVKTNND DVYWSFTKGA 960
PEVISEICNK STLPADFEEV LRCYTHNGYR VIACAGKTLP KRTWLYSQKV SREEVESNLE 1020
FLGFIIFQNK LKKETSETLK SLQDANIRTI MCTGDNILTA ISVGREAGLI QCSRVYVPSI 1080
NDTPLHGEPV IVWRDVNEPD KILDTKTLKP VKLGNNSVES LRECNYTLAV SGDVFRLLFR 1140
DENEIPEEYL NEILLNSSIY ARMSPDEKHE LMIQLQKLDY TVGFCGDGAN DCGALKAADV 1200
GISLSEAEAS VAAPFTSKIF NISCVLDVIR EGRAALVTSF ACFQYMSLYS AIQFITITIL 1260
YSRGSNLGDF QFLYIDLLLI VPIAICMSWS KSYEKIDKKR PSANLVSPKI LVPLLISVFL 1320
VFLFQFIPWI IVQKMSWYIK PIVGGDDAVQ SSDNTVLFFV SNFQYILTAI VLSVGPPYRE 1380
PMSKNFEFIV DITVSIGASL LLMTLDTESY LGKMLQLTPI SNSFTMFIIV WVILNYYAQL 1440
YIPPSIKGWL KKKKSSKKYK LLIQEEMKLK EV 1473
Keyword

KW-0007--Acetylation
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0460--Magnesium
KW-0472--Membrane
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0926--Vacuole

Interpro

IPR023299--ATPase_P-typ_cyto_domN
IPR018303--ATPase_P-typ_P_site
IPR008250--ATPase_P-typ_transduc_dom_A
IPR023214--HAD-like_dom
IPR006544--P-type_TPase_V
IPR001757--P_typ_ATPase

PROSITE

PS00154--ATPASE_E1_E2

Pfam

PF00122--E1-E2_ATPase
PF12409--P5-ATPase

Gene Ontology

GO:0000329--C:fungal-type vacuole membrane
GO:0005887--C:integral component of plasma membrane
GO:1990816--C:vacuole-mitochondrion membrane contact site
GO:0005524--F:ATP binding
GO:0019829--F:cation-transporting ATPase activity
GO:0046872--F:metal ion binding
GO:0098655--P:cation transmembrane transport
GO:0006874--P:cellular calcium ion homeostasis