dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0016730
Uniprot Accession Q12691; ATN5_YEAST; D6VS26; E9PAF4; P89901;
Genbank Protein ID NP_010323.3;
Genbank Nucleotide ID NM_001180346.3;
Protein Name Sodium transport ATPase 5
Protein Synonyms/Alias
Gene Name ENA5
Gene Synonyms/Alias YDR038C;YD9673.10c;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of sodium or lithium ions to allow salt tolerance.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
177KNFDTDESLLTGESLdbPTM 3.018407956; 16381945; 23193290
Sequence
(Fasta)
MSEGTVKENN NEEFNAYHTL TTEEAAEFIG TSLTEGLTQD ESLRRLKAVG ENTLGDDTKI 60
DYKAMVLHQV CNAMIMVLVI SMAISFAVRD WITGGVISFV IAVNVLIGLV QEYKATKTMN 120
SLKNLSSPNA HVIRNGKSET INSKDVVPGD ICLVKVGDTI PADLRLIETK NFDTDESLLT 180
GESLPVSKDA NLVFGKEEET SVGDRLNLAF SSSAVVKGRA KGIVIKTALN SEIGKIAKSL 240
QGDSGLISRD PSKSWLQNTW ISTKKVTGAF LGTNVGTPLH RKLSKLAVLL FWIAVLFAII 300
VMASQKFDVD KRVAIYAICV ALSMIPSSLV VVLTITMSVG AAVMVSRNVI VRKLDSLEAL 360
GAVNDICSDK TGTLTQGKML ARQIWIPRFG TITISNSDDP FNPNEGNVSL IPRFSPYEYS 420
HNEDGDVGIL QNFKDRLYEK DLPEDIDMDL FQKWLETATL ANIATVFKDD ATDCWKAHGD 480
PTEIAIQVFA TKMDLPHNAL TGEKSTNQSN ENDQSSLSQH NEKPGSAQFE HIAEFPFDST 540
VKRMSSVYYN NHNETYNIYG KGAFESIISC CSSWYGKDGV KITPLTDCDV ETIRKNVYSL 600
SNEGLRVLGF ASKSFTKDQV NDDQLKNITS NRATAESDLV FLGLIGIYDP PRNETAGAVK 660
KFHQAGINVH MLTGDFVGTA KAIAQEVGIL PTNLYHYSQE IVDSMVMTGS QFDGLSEEEV 720
DDLPVLPLVI ARCSPQTKVR MIEALHRRKK FCAMTGDGVN DSPSLKMANV GIAMGINGSD 780
VSKEASDIVL SDDNFASILN AVEEGRRMTD NIQKFVLQLL AENVAQALYL IIGLVFRDEN 840
GKSVFPLSPV EVLWIIVVTS CFPAMGLGLE KAAPDLMDRP PNDSEVGIFT WEVIIDTFAY 900
GIIMTGSCMA SFTGSLYGIN SGRLGHDCDG TYNSSCRDVY RSRSAAFATM TWCALILAWE 960
VVDMRRSFFR MHPDTDSPVK EFFRSIWGNQ FLFWSIIFGF VSAFPVVYIP VINDKVFLHK 1020
PIGAEWGLAI AFTIAFWIGA ELYKCGKRRY FKTQRAHNSE NDLERSSKHD PFEAYSTSTT 1080
LQSEINISVK H 1092
Keyword

KW-0067--ATP-binding
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0406--Ion transport
KW-1017--Isopeptide bond
KW-0460--Magnesium
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0915--Sodium
KW-0739--Sodium transport
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
KW-0832--Ubl conjugation

Interpro

IPR006068--ATPase_P-typ_cation-transptr_C
IPR004014--ATPase_P-typ_cation-transptr_N
IPR023299--ATPase_P-typ_cyto_domN
IPR018303--ATPase_P-typ_P_site
IPR023298--ATPase_P-typ_TM_dom
IPR008250--ATPase_P-typ_transduc_dom_A
IPR023214--HAD-like_dom
IPR006414--P-type_ATPase_IID
IPR001757--P_typ_ATPase

PROSITE

PS00154--ATPASE_E1_E2

Pfam

PF00689--Cation_ATPase_C
PF00690--Cation_ATPase_N
PF00122--E1-E2_ATPase
PF00702--Hydrolase

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0043231--C:intracellular membrane-bounded organelle
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0015662--F:ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
GO:0019829--F:cation-transporting ATPase activity
GO:0046872--F:metal ion binding
GO:0008554--F:sodium-exporting ATPase activity, phosphorylative mechanism
GO:0098655--P:cation transmembrane transport
GO:0006814--P:sodium ion transport
GO:0055085--P:transmembrane transport