dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016726
Uniprot Accession Q12674; ATC8_YEAST; D6VZY4;
Genbank Protein ID NP_013885.1;
Genbank Nucleotide ID NM_001182666.1;
Protein Name Probable phospholipid-transporting ATPase DNF3
Protein Synonyms/Alias
Gene Name DNF3
Gene Synonyms/Alias YMR162C;YM8520.11C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of phospholipids.
Phosphorylation Sites
 dbPAF PTMs: 33 (View all)
PositionPeptidesSourceReferences ( PMIDs )
13GQRRRSSSLRTQMFNcurated19823750
16RRSSSLRTQMFNKHLcurated19823750
43ELEDINESKTFSGSDcurated25315811
47INESKTFSGSDNNDKcurated25315811
49ESKTFSGSDNNDKDDcurated25315811
347DGETNLKSKQPHPELPhosphoGRID 2.0;curated19823750; 19795423; 22817900
608FEDNRDNTNSLRLPPcurated25315811
621PPKAHNGSSIDVVSIdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 26040289; 22369663;
622PKAHNGSSIDVVSIGdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 26040289; 22817900
627GSSIDVVSIGDQNVLPhosphoGRID 2.0;UniProt;curated19779198; 26040289; 22369663; 22817900; 25315811
651IEKGHRPSLDNFPKSdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated17287358; 16381945; 23193290; 19823750; 19779198; 19795423;
661NFPKSRNSIEYKGNScurated26040406; 25315811
677AIYTGRPSMRSLFGKPhosphoGRID 2.0;curated19779198; 22817900; 24961812; 25315811
680TGRPSMRSLFGKDNScurated24961812
690GKDNSHLSKQASVIScurated25315811
697SKQASVISPSETFSEcurated22817900; 24961812; 25315811; 20377248
699QASVISPSETFSENIdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
701SVISPSETFSENIKScurated22817900; 24961812; 20377248
703ISPSETFSENIKSSFdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
821NSQRKRMSVLVRMPNcurated22817900; 19547744
Sequence
(Fasta)		MGIADGQRRR SSSLRTQMFN KHLYDKYRGR TDDEIELEDI NESKTFSGSD NNDKDDRDET 60
SGNYAAEEDY EMEEYGSPDV SYSIITKILD TILDRRRTFH SKDGRHIPII LDHNAIEYKQ 120
AATKRDGHLI DERFNKPYCD NRITSSRYTF YSFLPRQLYA QFSKLANTYF FIVAVLQMIP 180
GWSTTGTYTT IIPLCVFMGI SMTREAWDDF RRHRLDKEEN NKPVGVLVKD GNNDAQEVYT 240
LPSSVVSSTA YLTKSAAAEN NPPLNDDRNS SQGHFLDTHF NNFELLKNKY NVHIHQKKWE 300
KLRVGDFVLL TQDDWVPADL LLLTCDGENS ECFVETMALD GETNLKSKQP HPELNKLTKA 360
ASGLANINAQ VTVEDPNIDL YNFEGNLELK NHRNDTIMKY PLGPDNVIYR GSILRNTQNV 420
VGMVIFSGEE TKIRMNALKN PRTKAPKLQR KINMIIVFMV FVVATISLFS YLGHVLHKKK 480
YIDQNKAWYL FQADAGVAPT IMSFIIMYNT VIPLSLYVTM EIIKVVQSKM MEWDIDMYHA 540
ETNTPCESRT ATILEELGQV SYIFSDKTGT LTDNKMIFRK FSLCGSSWLH NVDLGNSEDN 600
FEDNRDNTNS LRLPPKAHNG SSIDVVSIGD QNVLDRLGFS DAPIEKGHRP SLDNFPKSRN 660
SIEYKGNSSA IYTGRPSMRS LFGKDNSHLS KQASVISPSE TFSENIKSSF DLIQFIQRYP 720
TALFSQKAKF FFLSLALCHS CLPKKTHNES IGEDSIEYQS SSPDELALVT AARDLGYIVL 780
NRNAQILTIK TFPDGFDGEA KLENYEILNY IDFNSQRKRM SVLVRMPNQP NQVLLICKGA 840
DNVIMERLHD RELAAKKMAD ICTSTKERKD AEAELVLQQR KSLERMVDEE AMARTSLRNS 900
LSSVPRASLS LQAVRKSLSM KNSRTRDPEK QIDSIDQFLE TVKKSDQEIG SVVNKSRKSL 960
HKQQIEKYGP RISIDGTHFP NNNVPIDTRK EGLQHDYDTE ILEHIGSDEL ILNEEYVIER 1020
TLQAIDEFST EGLRTLVYAY KWIDIGQYEN WNKRYHQAKT SLTDRKIKVD EAGAEIEDGL 1080
NLLGVTAIED KLQDGVSEAI EKIRRAGIKM WMLTGDKRET AINIGYSCML IKDYSTVVIL 1140
TTTDENIISK MNAVSQEVDS GNIAHCVVVI DGATMAMFEG NPTYMSVFVE LCTKTDSVIC 1200
CRASPSQKAL MVSNIRNTDP NLVTLAIGDG ANDIAMIQSA DIGVGIAGKE GLQASRVSDY 1260
SIGQFRFLLK LLFVHGRYNY IRTSKFMLCT FYKEITFYFT QLIYQRYTMF SGSSLYEPWS 1320
LSMFNTLFTS LPVLCIGMFE KDLKPMTLLT VPELYSYGRL SQGFNWLIFM EWVILATTNS 1380
LIITFLNVVM WGMSSLSDNT MYPLGLINFT AIVALINVKS QFVEMHNRNW LAFTSVVLSC 1440
GGWLVWCCAL PILNNTDQIY DVAYGFYNHF GKDITFWCTS LVLALLPITL DIVYKTFKVM 1500
IWPSDSDIFA ELEQKSDIRK KLELGAYSEM RQGWTWDKDP STFTRYTDKV LSRPRTNSRA 1560
SAKTHNSSIY SMSNGNVDHS SKKNFFGNSS KKSSERYEVL PSGKLIKRPS LKTQSSKDSI 1620
GGNITTKLTK KLKLPSRNVE DEDVNQIIQA RLKDLE 1657
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0460--Magnesium
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR023299--ATPase_P-typ_cyto_domN
IPR018303--ATPase_P-typ_P_site
IPR008250--ATPase_P-typ_transduc_dom_A
IPR023214--HAD-like_dom
IPR006539--P-type_ATPase_IV
IPR032631--P-type_ATPase_N
IPR001757--P_typ_ATPase
IPR032630--P_typ_ATPase_c
PROSITE

PS00154--ATPASE_E1_E2
Pfam

PF00122--E1-E2_ATPase
PF16212--PhoLip_ATPase_C
PF16209--PhoLip_ATPase_N
Gene Ontology

GO:0016021--C:integral component of membrane
GO:0070867--C:mating projection tip membrane
GO:0005886--C:plasma membrane
GO:0005802--C:trans-Golgi network
GO:0030140--C:trans-Golgi network transport vesicle
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004012--F:phospholipid-translocating ATPase activity
GO:0032456--P:endocytic recycling
GO:0006886--P:intracellular protein transport
GO:0045332--P:phospholipid translocation
GO:0006892--P:post-Golgi vesicle-mediated transport
GO:0000749--P:response to pheromone involved in conjugation with cellular fusion