dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0016723 | ||||||||
| Uniprot Accession | Q12524; PCD1_YEAST; D6VYE6; | ||||||||
| Genbank Protein ID | NP_013252.1; | ||||||||
| Genbank Nucleotide ID | NM_001182038.1; | ||||||||
| Protein Name | Peroxisomal coenzyme A diphosphatase 1, peroxisomal | ||||||||
| Protein Synonyms/Alias | |||||||||
| Gene Name | PCD1 | ||||||||
| Gene Synonyms/Alias | YLR151C;L9634.8; | ||||||||
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) | ||||||||
| NCBI Taxa ID | 559292 | ||||||||
| Functional Description (View all) |
Coenzyme A diphosphatase which mediates the cleavage of CoA into 3',5'-ADP and 4'-phosphopantetheine. Has a strong preference for oxidized CoA disulfide (CoASSCoA) as substrate. May be required to remove potentially toxic oxidized CoA disulfide to maintain the capacity for beta-oxidation of fatty acids. Can degrade 8-oxo-dGTP in vitro; however, such activity may not be relevant in vivo. | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
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| Sequence (Fasta) | MILSQRRMLS SKQLIENLIR YKFHKTPYTR SSIWPFKRNS AVIILLFIGM KGELRVLLTK 60 RSRTLRSFSG DVSFPGGKAD YFQETFESVA RREAEEEIGL PHDPEVLHKE FGMKLDNLVM 120 DMPCYLSRTF LSVKPMVCFL YKDKLEKHED KYKVPLDIRK FFGKLNPGET SSLFSVPLND 180 LVIHLLPEAD EDVKSYQAEY FERKEYKLNW GGIKWLIMHY HFHVANNNEM PWLQTIEDLS 240 SSDEDGVDGG IFRFRDLWGL TCKILFDVSC IANGLMDEKL KGELGHEDLI VGLHDYGNQM 300 QPNGRSEWEI GMINGDRNLK YSDVIPEYYM KHLLECRSLW 341 |
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| Keyword | KW-0181--Complete proteome |
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| Interpro | IPR000086--NUDIX_hydrolase_dom |
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| PROSITE | |||||||||
| Pfam | PF00293--NUDIX |
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| Gene Ontology | GO:0005777--C:peroxisome |