dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016714
Uniprot Accession Q12513; TMA17_YEAST; D6VRP0;
Genbank Protein ID NP_010173.1;
Genbank Nucleotide ID NM_001180169.1;
Protein Name Translation machinery-associated protein 17
Protein Synonyms/Alias ATPase-dedicated chaperone of 17 kDa;ADC17;
Gene Name TMA17
Gene Synonyms/Alias YDL110C;D2320;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 ATPase-dedicated chaperone that assists the formation of the RPT6-RPT3 ATPase pair, an early step in proteasome assembly. Plays a key role in maintaining homeostatic proteasome levels and adjusting proteasome assembly when demands increase, such as during proteasome stresses. Function overlaps with RPN14.
Phosphorylation Sites
 dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
24KTAISGMSDMELAQIdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19366988
33MELAQIKTEIENSINcurated22817900
38IKTEIENSINHLQRScurated22817900
45SINHLQRSNARLGKYcurated22817900
52SNARLGKYIAKLEGAcurated26040406
68DRLEADDSDDLENIDdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 17563356; 18407956; 16381945; 23193290; 21177495;
76DDLENIDSGDLALYKPhosphoGRID 2.0;curated19779198; 22817900; 19547744
127EVEAKDNTNKGPDVDcurated22817900
Sequence
(Fasta)		MCSAGGIRRP IQIEEFKTAI SGMSDMELAQ IKTEIENSIN HLQRSNARLG KYIAKLEGAD 60
DRLEADDSDD LENIDSGDLA LYKDSVRENE IVLNNYNERV DALEQETVYR KTGHGKSKHE 120
VEAKDNTNKG PDVDMDNSNV DVVTPNSIFI 151
Keyword

KW-0143--Chaperone
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro
PROSITE
Pfam
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0030674--F:protein binding, bridging
GO:0070682--P:proteasome regulatory particle assembly