dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0016711
Uniprot Accession Q12509; ARP6_YEAST; D6VY85;
Genbank Protein ID NP_013186.1;
Genbank Nucleotide ID NM_001181972.1;
Protein Name Actin-like protein ARP6
Protein Synonyms/Alias
Gene Name ARP6
Gene Synonyms/Alias YLR085C;L2393;L9449.13;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability.
Phosphorylation Sites
dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
3-----METPPIVIDNcurated26040406
12PIVIDNGSYEIKFGPcurated26040406
13IVIDNGSYEIKFGPScurated26040406; 22817900
20YEIKFGPSTNKKPFRcurated22817900
Sequence
(Fasta)
METPPIVIDN GSYEIKFGPS TNKKPFRALN ALAKDKFGTS YLSNHIKNIK DISSITFRRP 60
HELGQLTLWE LESCIWDYCL FNPSEFDGFD LKEGKGHHLV ASESCMTLPE LSKHADQVIF 120
EEYEFDSLFK SPVAVFVPFT KSYKGEMRTI SGKDEDIDIV RGNSDSTNST SSESKNAQDS 180
GSDYHDFQLV IDSGFNCTWI IPVLKGIPYY KAVKKLDIGG RFLTGLLKET LSFRHYNMMD 240
ETILVNNIKE QCLFVSPVSY FDSFKTKDKH ALEYVLPDFQ TSFLGYVRNP RKENVPLPED 300
AQIITLTDEL FTIPETFFHP EISQITKPGI VEAILESLSM LPEIVRPLMV GNIVCTGGNF 360
NLPNFAQRLA AELQRQLPTD WTCHVSVPEG DCALFGWEVM SQFAKTDSYR KARVTREEYY 420
EHGPDWCTKH RFGYQNWI 439
Keyword

KW-0010--Activator
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation

Interpro

IPR004000--Actin
IPR030054--Arp6

PROSITE
Pfam

PF00022--Actin

Gene Ontology

GO:0005737--C:cytoplasm
GO:0031011--C:Ino80 complex
GO:0035267--C:NuA4 histone acetyltransferase complex
GO:0034399--C:nuclear periphery
GO:0000812--C:Swr1 complex
GO:0031491--F:nucleosome binding
GO:0006338--P:chromatin remodeling
GO:0006281--P:DNA repair
GO:0043486--P:histone exchange
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated