dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0016709
Uniprot Accession Q12504; RKM4_YEAST; D6VSN7; Q07015;
Genbank Protein ID NP_010543.1;
Genbank Nucleotide ID NM_001180565.1;
Protein Name Ribosomal lysine N-methyltransferase 4
Protein Synonyms/Alias SET domain-containing protein 7;
Gene Name RKM4
Gene Synonyms/Alias RMS1;SET7;YDR257C;YD9320A.07C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that monomethylates 60S ribosomal protein L42 (RPL42A and RPL42B) at 'Lys-55'.
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
44QGRAVVATQKIKKDEdbPTM 3.0;SysPTM 2.018407956; 16381945; 23193290; 19366988
59TLFKIPRSSVLSVTTcurated19823750
60LFKIPRSSVLSVTTScurated19823750
Sequence
(Fasta)
MDDFSRDTEN FVCWLKTTAE IEVSPKIEIK DLCCDNQGRA VVATQKIKKD ETLFKIPRSS 60
VLSVTTSQLI KDYPSLKDKF LNETGSWEGL IICILYEMEV LQERSRWAPY FKVWNKPSDM 120
NALIFWDDNE LQLLKPSLVL ERIGKKEAKE MHERIIKSIK QIGGEFSRVA TSFEFDNFAY 180
IASIILSYSF DLEMQDSSVN ENEEEETSEE ELENERYLKS MIPLADMLNA DTSKCNANLT 240
YDSNCLKMVA LRDIEKNEQV YNIYGEHPNS ELLRRYGYVE WDGSKYDFGE VLLENIVEAL 300
KETFETNTEF LDRCIDILRN NANIQEFLEG EEIVLDSYDC YNNGELLPQL ILLVQILTIL 360
CQIPGLCKLD IKAMERQVER IVKKCLQLIE GARATTNCSA TWKRCIMKRL ADYPIKKCVS 420
IEKPSKGNSL TREELRDVMA RRVLKSEIDS LQVCEETIDK NYKVIPDEKL LTNILKRKLT 480
EEEKSSVKRP CVKK 495
Keyword

KW-0181--Complete proteome
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase

Interpro

IPR011383--N-lys_methylase_SETD6
IPR001214--SET_dom

PROSITE

PS50280--SET

Pfam

PF00856--SET

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0016279--F:protein-lysine N-methyltransferase activity
GO:0018026--P:peptidyl-lysine monomethylation