dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016706
Uniprot Accession Q12500; AVL9_YEAST; D6VYB2;
Genbank Protein ID NP_013215.1;
Genbank Nucleotide ID NM_001182001.1;
Protein Name Late secretory pathway protein AVL9
Protein Synonyms/Alias APL2 VPS1 synthetic lethal protein 9;
Gene Name AVL9
Gene Synonyms/Alias YLR114C;L2941;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Functions in the late secretory pathway. Required for the generation of secretory vesicles as well as for actin polarization and polarized growth.
Phosphorylation Sites
 dbPAF PTMs: 16
PositionPeptidesSourceReferences ( PMIDs )
493HNLKRSSSNSSSNKNcurated25315811
504SNKNGHQSEEDIKDQPhosphoGRID 2.0;PHOSIDA;curated19823750; 19795423; 21081558; 26040289; 22369663; 22817900;
513EDIKDQESIESKKSVPhosphoGRID 2.0;PHOSIDA;curated19823750; 19795423; 21081558; 26040289; 22817900; 24961812;
516KDQESIESKKSVSQIPhosphoGRID 2.0;PHOSIDA;curated19823750; 19795423; 21081558; 26040289; 22817900; 24961812
519ESIESKKSVSQISVNdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 21126336; 20702584; 19823750;
521IESKKSVSQISVNPGdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 22369663; 22817900;
524KKSVSQISVNPGKNTdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19779198; 21081558; 19366988;
552YFNKPKNTANEDVTEPhosphoGRID 2.021126336
560ANEDVTESTEDLKNRdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated17563356; 18407956; 16381945; 23193290; 19366988; 26040406;
561NEDVTESTEDLKNRSdbPTM 3.0;SysPTM 2.018407956; 16381945; 23193290; 19366988
571LKNRSKTSNAIQKAMPhosphoGRID 2.019779198
664ENGDKEDSQDFSNGFcurated25315811
679TDVTNINTDHDKENEcurated25315811
701ENFNEDETVADKDIEcurated24961812; 25315811
717GPESNKNSDSKTDIYcurated19823750
719ESNKNSDSKTDIYENcurated24961812
Sequence
(Fasta)		MDEHEEAVIF GICLVDFHHK RGPEIEYWYG LPEGTQSAEL WPNLPFQALP DGSHSFEETF 60
TYFTLLYDER RQRSPPNGAT DLSDDSINDN TTLFAISCSR QIKSDELVTK DKDVTRSTVQ 120
KAIVVISRQP IFGQIKDKLS IVTNAFFLQH DFGDRKIIQS LYENLKSIYT PASLVRNAEN 180
RLYIGLCLRK ILHDFKRNAL VLLKAIMLEK KIIVYGNDVE ALCNLQFGLI SLIPDLMSNL 240
QDSGSPQLFQ DISKLNVVDS FKSSNRESVL RFLGFPLPIF EKGGLFSPYT PLQQMNDIRS 300
ERTLFFMIGS SNTLLAEQKE ELCHIFVNTD NSTVDILDKT LNPVLQLSSH DKKWIESISG 360
IVSDTWNEND DETPKNSQFE GSEDFIRWQF EDYLTGLLSS VKLSDYLDLH KENDQALKTI 420
PEDMLNSNPV HLFNLNWVQS WKETQNFLIF NSRTDDRLFD LFPPKHIYNG ADTLSLLQQR 480
FLATFHNLKR SSSNSSSNKN GHQSEEDIKD QESIESKKSV SQISVNPGKN TDKPAANLWN 540
SWKEYFNKPK NTANEDVTES TEDLKNRSKT SNAIQKAMMG LGLHYKPDAE TDQQSEEVGN 600
SEDNEDDDTD EDSEDDDDDG GDDDDSEDDD DDDDGEGDEN GDDGEGDENG DDGEGDENGD 660
KEDSQDFSNG FTDVTNINTD HDKENEQNFE GNAENFNEDE TVADKDIEGG PESNKNSDSK 720
TDIYENDRNV EDSSKTRNTV KKSNEEGGAN DAAIGNCVQD EEKL 765
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR018307--ABL9/DENND6_dom
PROSITE
Pfam

PF09794--Avl9
Gene Ontology

GO:0005737--C:cytoplasm
GO:0006892--P:post-Golgi vesicle-mediated transport