dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016705
Uniprot Accession Q12499; NOP58_YEAST; D6W309;
Genbank Protein ID NP_014955.1;
Genbank Nucleotide ID NM_001183730.1;
Protein Name Nucleolar protein 58
Protein Synonyms/Alias Nucleolar protein 5;
Gene Name NOP58
Gene Synonyms/Alias NOP5;YOR310C;O6108;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Required for pre-18S rRNA processing. May bind microtubules.
Phosphorylation Sites
 dbPAF PTMs: 14
PositionPeptidesSourceReferences ( PMIDs )
3-----MAYVLTETSAcurated26040406
6--MAYVLTETSAGYAcurated26040406
8MAYVLTETSAGYALLcurated26040406
25SDKKIYKSSSLIQDLcurated22817900
27KKIYKSSSLIQDLDScurated22817900; 25315811; 19547744
219MGIRSKASETDLSEIcurated25315811
312SLISLAKSPASTIQIcurated24961812
399AKVENRLSQLEGRDLdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 26040406; 24961812;
408LEGRDLRTTPKVVREcurated24961812
409EGRDLRTTPKVVREAcurated24961812
438ADTAKAASDSESDSDPhosphoGRID 2.0;PHOSIDA;curated19684113; 21081558; 22817900; 19795423
440TAKAASDSESDSDDEPHOSIDA;curated21081558; 22817900; 19795423
442KAASDSESDSDDEEEPHOSIDA;curated21081558; 22817900; 19795423
444ASDSESDSDDEEEEKPHOSIDA;curated21081558; 22817900; 19795423
Sequence
(Fasta)		MAYVLTETSA GYALLKASDK KIYKSSSLIQ DLDSSDKVLK EFKIAAFSKF NSAANALEEA 60
NSIIEGKVSS QLEKLLEEIK KDKKSTLIVS ETKLANAINK LGLNFNVVSD AVTLDIYRAI 120
KEYLPELLPG MSDNDLSKMS LGLAHSIGRH KLKFSADKVD VMIIQAIALL DDLDKELNTY 180
AMRCKEWYGW HFPELAKIVT DSVAYARIIL TMGIRSKASE TDLSEILPEE IEERVKTAAE 240
VSMGTEITQT DLDNINALAE QIVEFAAYRE QLSNYLSARM KAIAPNLTQL VGELVGARLI 300
AHSGSLISLA KSPASTIQIL GAEKALFRAL KTKHDTPKYG LLYHASLVGQ ATGKNKGKIA 360
RVLAAKAAVS LRYDALAEDR DDSGDIGLES RAKVENRLSQ LEGRDLRTTP KVVREAKKVE 420
MTEARAYNAD ADTAKAASDS ESDSDDEEEE KKEKKEKKRK RDDDEDSKDS KKAKKEKKDK 480
KEKKEKKEKK EKKEKKEKKE KKSKKEKKEK K 512
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0687--Ribonucleoprotein
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
Interpro

IPR012974--NOP5_N
IPR002687--Nop_dom
IPR012976--NOSIC
PROSITE

PS51358--NOP
Pfam

PF01798--Nop
PF08156--NOP5NT
Gene Ontology

GO:0031428--C:box C/D snoRNP complex
GO:0005730--C:nucleolus
GO:0032040--C:small-subunit processome
GO:0030515--F:snoRNA binding
GO:0017069--F:snRNA binding
GO:0000480--P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5
8S rRNA, L--U-rRNA)
GO:0000447--P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5
8S rRNA an-- LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5
8S rRNA, L--U-rRNA)
GO:0000472--P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5
8S rRNA, L--U-rRNA)
GO:0000154--P:rRNA modification
GO:0006364--P:rRNA processing
GO:0006608--P:snRNP protein import into nucleus