dbPAF Protein Information
Tag | Content | ||||||||
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dbPAF ID | dbPAF-0016701 | ||||||||
Uniprot Accession | Q12493; NKP1_YEAST; D6VT17; | ||||||||
Genbank Protein ID | NP_010671.4; | ||||||||
Genbank Nucleotide ID | NM_001180691.3; | ||||||||
Protein Name | Central kinetochore subunit NKP1 | ||||||||
Protein Synonyms/Alias | Non-essential kinetochore protein 1; | ||||||||
Gene Name | NKP1 | ||||||||
Gene Synonyms/Alias | YDR383C; | ||||||||
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) | ||||||||
NCBI Taxa ID | 559292 | ||||||||
Functional Description (View all) |
Component of the central kinetochore, which mediates the attachment of the centromere to the mitotic spindle by forming essential interactions between the microtubule-associated outer kinetochore proteins and the centromere-associated inner kinetochore proteins. Required for establishing bipolar spindle-microtubule attachments and proper chromosome segregation. | ||||||||
Phosphorylation Sites |
dbPAF PTMs: 1
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Sequence (Fasta) | MTDTYNSISN FIENELTALL SSDDYLMDDL AGELPNEVCR LLKAQVIEKR KDAMSRGKQD 60 LLSKEIYDNE SELRASQSQQ IMELVGDIPK YSLGSELRNR VEGEPQSTSI ERLIEDVLKL 120 PQMEVADEEE VEVENDLKVL SEYSNLRKDL ILKCQALQIG ESKLSDILSQ TNSINSLTTS 180 IKEASEDDDI SEYFATYNGK LVVALEEMKL LLEEAVKTFG NSPEKREKIK KILSELKK 239 |
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Keyword | KW-0131--Cell cycle |
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Interpro | |||||||||
PROSITE | |||||||||
Pfam | |||||||||
Gene Ontology | GO:0000777--C:condensed chromosome kinetochore |