dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0016696 |
| Uniprot Accession | Q12482; AGC1_YEAST; D6W431; |
| Genbank Protein ID | NP_015346.1; |
| Genbank Nucleotide ID | NM_001184118.1; |
| Protein Name | Mitochondrial aspartate-glutamate transporter AGC1 |
| Protein Synonyms/Alias | Aspartate-glutamate carrier 1; |
| Gene Name | AGC1 |
| Gene Synonyms/Alias | YPR021C;YP9367.01C; |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID | 559292 |
| Functional Description (View all) |
Calcium-dependent mitochondrial aspartate and glutamate carrier. Transport of glutamate in mitochondria is required for mitochondrial transamination reactions and ornithine synthesis. Plays also a role in malate-aspartate NADH shuttle, which is critical for growth on acetate and fatty acids. |
| Phosphorylation Sites |
dbPAF PTMs: 5 |
| Sequence (Fasta) | MEQINSNSRK KKQQLEVFKY FASVLTKEDK PISISNGMLD MPTVNSSKLT AGNGKPDTEK 60 LTGELILTYD DFIELISSSK TIYSKFTDHS FNLNQIPKNV FGCIFFAIDE QNKGYLTLND 120 WFYFNNLLEY DNYHLIILYE FFRKFDVENL KAKQKKELGS SSFNLKAADD RIKSINYGNR 180 FLSFDDLLLN LNQFKDTIRL LHESIDDNFV KDNKLLLDWN DFRFLKFYKC YHENEEYLSL 240 NSLVTILQND LKNEKIFIGF DRLAQMDSQG HRLALSKNQL TYLLRLFYSH RVSADIFSSL 300 NLSNTELLKA DNNSIPYNVF KDIFYLFQNF DLLNQIFHKY VTENNLNEQD IREQIVTKND 360 FMTVLNAQYN KVNNIIEFSP SQINLLFSIV ANSKENRRLR KRNQDRDDEL LNDHHYDSDI 420 DFFIHNEYLH GVSRSRKNLE SFNDYYHDLS DGFDQDSGVK KASKASTGLF ESVFGGKKDK 480 ATMRSDLTIE DFMKILNPNY LNDLVHQMEL QKNQNESLYI NYYFYPIFDS LYNFSLGSIA 540 GCIGATVVYP IDFIKTRMQA QRSLAQYKNS IDCLLKIISR EGIKGLYSGL GPQLIGVAPE 600 KAIKLTVNDF MRNRLTDKNG KLSLFPEIIS GASAGACQVI FTNPLEIVKI RLQVQSDYVG 660 ENIQQANETA TQIVKKLGLR GLYNGVAACL MRDVPFSAIY FPTYAHLKKD LFDFDPNDKT 720 KRNRLKTWEL LTAGAIAGMP AAFLTTPFDV IKTRLQIDPR KGETKYNGIF HAIRTILKEE 780 SFRSFFKGGG ARVLRSSPQF GFTLAAYELF KGFIPSPDNK LKSREGRKRF CIDDDAGNEE 840 TVVHSNGELP QQKFYSDDRK HANYYYKSCQ IAKTFIDLDN NFSRFDSSVY KNFQEHLRSI 900 NG 903 |
| Keyword | KW-0029--Amino-acid transport |
| Interpro | IPR002067--Mit_carrier |
| PROSITE | PS50920--SOLCAR |
| Pfam | PF00153--Mito_carr |
| Gene Ontology | GO:0016021--C:integral component of membrane |