dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016694
Uniprot Accession Q12480; ETFA_YEAST; D6W415;
Genbank Protein ID NP_015329.1;
Genbank Nucleotide ID NM_001184101.1;
Protein Name Probable electron transfer flavoprotein subunit alpha, mitochondrial
Protein Synonyms/Alias
Gene Name AIM45
Gene Synonyms/Alias YPR004C;LPZ4C;YP9723.04C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).
Phosphorylation Sites
 dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
76EALKSSYSCSNLEKLcurated22817900
89KLVIFEDSKLDTCLPcurated26040289
245ETFEKLLSPLADVLHcurated22369663
Sequence
(Fasta)		MFKSLAAVLP RASKAKFLQK NYASTLAFIE SSKDGSVSRS SLSLLAAAQK LSNPITAVIT 60
GSKAEKTAEA LKSSYSCSNL EKLVIFEDSK LDTCLPEQLT PLLVKLLKGG DYSHFVVSNS 120
SVGKSVLPRV GALLDVQPVC EVTVIKDPKT FIRPIYAGNI ISTIECQAEK KLLIIRASAF 180
PPIAEGSMDS VTIEKRTDIP PCDLNVTWVK TILTKSERPE LTSAQNVVTG GRALKDKETF 240
EKLLSPLADV LHAAIGATRA SVDNGLCDNS LQIGQTGKVV APNLYIAIGV SGAVQHLAGM 300
KDSKVIVAIN NDPDAPIFNV ADYGLQGDLY KIVPELTEKL GKYK 345
Keyword

KW-0181--Complete proteome
KW-0249--Electron transport
KW-0274--FAD
KW-0285--Flavoprotein
KW-0496--Mitochondrion
KW-1185--Reference proteome
KW-0809--Transit peptide
KW-0813--Transport
Interpro

IPR029035--DHS-like_NAD/FAD-binding_dom
IPR001308--ETF_a
IPR014730--ETF_a/b_N
IPR014731--ETF_asu_C
IPR018206--ETF_asu_C_CS
IPR014729--Rossmann-like_a/b/a_fold
PROSITE

PS00696--ETF_ALPHA
Pfam

PF01012--ETF
PF00766--ETF_alpha
Gene Ontology

GO:0005759--C:mitochondrial matrix
GO:0005739--C:mitochondrion
GO:0003995--F:acyl-CoA dehydrogenase activity
GO:0009055--F:electron carrier activity
GO:0000062--F:fatty-acyl-CoA binding
GO:0050660--F:flavin adenine dinucleotide binding
GO:0052890--F:oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor
GO:0033539--P:fatty acid beta-oxidation using acyl-CoA dehydrogenase
GO:0055088--P:lipid homeostasis