dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0016689
Uniprot Accession Q12469; SKM1_YEAST; D6W1V4; E9P934; Q06940;
Genbank Protein ID NP_014528.1;
Genbank Nucleotide ID NM_001183367.1;
Protein Name Serine/threonine-protein kinase SKM1
Protein Synonyms/Alias Protein kinase 75490 D;
Gene Name SKM1
Gene Synonyms/Alias YOL113W;HRA655;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
May be involved in cellular signaling or cytoskeletal functions. May play a role in morphogenetic control.
Phosphorylation Sites
dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
81TDQKENISPINSYFYPhosphoGRID 2.020489023
169YDDWNRNSKAVIKALPhosphoGRID 2.020489023
231RTLRKGKTDSILPVYcurated25315811
249LKPFPRPSDDDYKFTPhosphoGRID 2.0;curated20489023; 25315811
275RVHVSKESTADSQTKPhosphoGRID 2.020489023
276VHVSKESTADSQTKQPhosphoGRID 2.020489023
411AIKQIRLSEQPKKQLPhosphoGRID 2.021126336
Sequence
(Fasta)
MKGVKKEGWI SYKVDGLFSF LWQKRYLVLN DSYLAFYKSD KCNEEPVLSV PLTSITNVSR 60
IQLKQNCFEI LRATDQKENI SPINSYFYES NSKRSIFIST RTERDLHGWL DAIFAKCPLL 120
SGVSSPTNFT HKVHVGFDPK VGNFVGVPDS WAKLLQTSEI TYDDWNRNSK AVIKALQFYE 180
DYNGLDTMQF NDHLNTSLDL KPLKSPTRYI INKRTNSIKR SVSRTLRKGK TDSILPVYQS 240
ELKPFPRPSD DDYKFTNIED NKVREEGRVH VSKESTADSQ TKQLGKKEQK VIQSHLRRHD 300
NNSTFRPHRL APSAPATKNH DSKTKWHKED LLELKNNDDS NEIIMKMKTV AIDVNPRPYF 360
QLVEKAGQGA SGAVYLSKRI KLPQENDPRF LKSHCHRVVG ERVAIKQIRL SEQPKKQLIM 420
NELLVMNDSR QENIVNFLEA YIIDDEELWV IMEYMEGGCL TDILDAVARS NTGEHSSPLN 480
ENQMAYIVKE TCQGLKFLHN KKIIHRDIKS DNILLNSQGL VKITDFGFCV ELTEKRSKRA 540
TMVGTPYWMA PEIVNQKGYD EKVDVWSLGI MLIEMIEGEP PYLNEDPLKA LYLIANNGSP 600
KLRHPESVSK QTKQFLDACL QVNVESRASV RKLLTFEFLS MACSPEQLKV SLKWH 656
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR000095--CRIB_dom
IPR011009--Kinase-like_dom
IPR011993--PH/PTB_dom
IPR001849--PH_domain
IPR000719--Prot_kinase_dom
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS50108--CRIB
PS50003--PH_DOMAIN
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00786--PBD
PF00169--PH
PF00069--Pkinase

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0048365--F:Rac GTPase binding
GO:0030036--P:actin cytoskeleton organization
GO:0032147--P:activation of protein kinase activity
GO:0016477--P:cell migration
GO:0000920--P:cell separation after cytokinesis
GO:0010629--P:negative regulation of gene expression
GO:1990872--P:negative regulation of sterol import by negative regulation of transcription from RNA polymerase II promoter
GO:0006468--P:protein phosphorylation
GO:0042981--P:regulation of apoptotic process
GO:0043408--P:regulation of MAPK cascade
GO:0007346--P:regulation of mitotic cell cycle
GO:0007266--P:Rho protein signal transduction
GO:0023014--P:signal transduction by protein phosphorylation
GO:0035376--P:sterol import
GO:0031098--P:stress-activated protein kinase signaling cascade