dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0016688 |
| Uniprot Accession | Q12468; CSN5_YEAST; D6VRD8; |
| Genbank Protein ID | NP_010065.2; |
| Genbank Nucleotide ID | NM_001180276.1; |
| Protein Name | COP9 signalosome complex subunit 5 |
| Protein Synonyms/Alias | |
| Gene Name | RRI1 |
| Gene Synonyms/Alias | CSN5;JAB1;YDL216C;D0888; |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID | 559292 |
| Functional Description (View all) |
Catalytic component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes (By similarity). The CSN complex is involved in the regulation of the mating pheromone response. |
| Phosphorylation Sites |
dbPAF PTMs: 4 |
| Sequence (Fasta) | MSLSNKTVKE LRQLLKERYT VEDELTESIA LSSMRFKPSQ EPEFHALSQS SLLKTKLKQQ 60 SSTDIPSYTH VLISKLSCEK ITHYAVRGGN IEIMGILMGF TLKDNIVVMD CFNLPVVGTE 120 TRVNAQLESY EYMVQYIDEM YNHNDGGDGR DYKGAKLNVV GWFHSHPGYD CWLSNIDIQT 180 QDLNQRFQDP YVAIVVDPLK SLEDKILRMG AFRTIESKSD DNSATSYYEL ETIIFDSELN 240 RALFETKLNL HCVIEDDESE QISLNRLIDS MKQYSYLMDS KNVRTRIKLA TTSERVSNEN 300 KKNIDYQNRS TRSQFCLNTQ RGDSTETSSF GSMFSGDNTS DVDMEDRNLT EFDSTDTSLC 360 INGEPSIHVN RVERSSRSTD NFHNSKKRMN SNQERCHDEG NDMLQRNVLE TDYARAKNRI 420 LASKIKQYER LRFYKDTFTL 441 |
| Keyword | KW-0181--Complete proteome |
| Interpro | IPR000555--JAMM/MPN+_dom |
| PROSITE | |
| Pfam | PF01398--JAB |
| Gene Ontology | GO:0008180--C:COP9 signalosome |