dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016687
Uniprot Accession Q12466; TCB1_YEAST; D6W2E8;
Genbank Protein ID NP_014729.1;
Genbank Nucleotide ID NM_001183505.1;
Protein Name Tricalbin-1
Protein Synonyms/Alias
Gene Name TCB1
Gene Synonyms/Alias YOR086C;YOR3141c;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 May play a role in membrane trafficking.
Phosphorylation Sites
 dbPAF PTMs: 15
PositionPeptidesSourceReferences ( PMIDs )
44TESSKSVSSEKAAHAPhosphoPep 2.019060867
45ESSKSVSSEKAAHAScurated26040406
59SDESFKRSIHEASYVPhosphoGRID 2.0;curated19779198; 22817900; 24961812
142FFVIVITSLLYRTSAcurated26040289
145IVITSLLYRTSAKKYcurated26040289
845VKELEDMYSNRQKLDcurated25315811
846KELEDMYSNRQKLDLcurated25315811
920KELDKSITTFRVAKNcurated24961812
1000DLTIMSRSAENLIASdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19779198; 19366988; 26040289;
1067IKVMDWDSTSADDTIcurated22817900
1068KVMDWDSTSADDTIGcurated22817900
1069VMDWDSTSADDTIGTcurated24961812
1146GTGLKAGTTVIGGGVPhosphoGRID 2.0;curated21126336; 19779198; 26040406; 22817900; 23825934
1147TGLKAGTTVIGGGVGPhosphoGRID 2.0;curated21126336; 19779198; 26040406; 22817900; 23825934; 20377248
1169GVFGGLGSLTNHKKNcurated24961812
Sequence
(Fasta)		MAKEDTGVTA PKKPETAQVA NINGIDKLEP PKTKEETESS KSVSSEKAAH ASDESFKRSI 60
HEASYVGWKQ IGGWEDKDEL TLDDELMDMT RETFLDNIIP DSLYGDWYHS VAIFFIGGVA 120
SFALGHYKFS MGSAFFVIVI TSLLYRTSAK KYRGSIRELV QKEFTVQKVE NDYESLEWLN 180
AFLDKYWPIL EPSVSQLIVQ QANEQMATNE AIPKFITQLW IDELTLGVKP PRVDLVKTFQ 240
NTASDVVVMD WGISFTPHDL CDMSAKQVRN YVNELAVVKA KIFGITIPVS VSDIAFKAHA 300
RVKFKLMTPF PHVETVNIQL LKVPDFDFVA TLFGRSIFNW EILAIPGLMT LIQKMAKKYM 360
GPILLPPFSL QLNIPQLLSG SNLSIGILEI TVKNAKGLKR TSSILNESID PYLSFEFNDI 420
SIAKTRTVRD TLNPVWDETL YVLLNSFTDP LTISVYDKRA KLKDKVLGRI QYNLNTLHDK 480
TTQRNLKAQF LRNSKPVGEL TFDLRFFPTL EEKKLPDGSV EELPDLNTGI AKVVVEEGSR 540
FAEEEQKVTA YVEVYLNAKL VLTTGKATDT GTLKWNSDYE AVIADRRKTR YKFVVKDGKG 600
EEIGSTIQTL NDLIDRSQVN KNLIPLKNQK GDIKITTYWR PVRLEIGSNS VAYTPPIGAI 660
RVFIEKANDL RNLEKFGTID PYCKVLVNGL SKGRTDFKSQ TLNPVWNQVI YVAVTSPNQR 720
ITLQCMDVET VNKDRSLGEF NVNVQDLFKK DENDKYEETI DEKAKVGRLV MPKKKPKGTI 780
TYYTSFYPAL PVLTLEEIQD LDKVNKKKKA LELRKSAIDE KKISKEDKAK FDQEWNEVKE 840
LEDMYSNRQK LDLPELLQYN QGVLAVTVLN GELPDSGLYV QAFFDDNGHP RFVSPRIPSR 900
IVKNGWSGDV IIKELDKSIT TFRVAKNKNY NRVEKCVCEV ELPTQELVKN CYYKPSILHL 960
SGEGSAKLML QISWFPIDTK QLPANDLITN SGDLTIMSRS AENLIASDLN GYSDPYLKYY 1020
INNEEDCAYK TKVVKKTLNP KWNDEGTIQI NNRLNDVLRI KVMDWDSTSA DDTIGTAEIP 1080
LNKVKVEGTT ELDVPVEGLE NAGQDGGMLH LAFSFKPRYT ISVSKREKKV GDIASKGLGT 1140
GLKAGTTVIG GGVGAIGKIK KGVFGGLGSL TNHKKNHEMG EEETKF 1187
Keyword

KW-0106--Calcium
KW-0111--Calcium/phospholipid-binding
KW-1003--Cell membrane
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0446--Lipid-binding
KW-0472--Membrane
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR000008--C2_dom
IPR017147--Tricalbin
PROSITE

PS50004--C2
Pfam

PF00168--C2
Gene Ontology

GO:0032541--C:cortical endoplasmic reticulum
GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0005544--F:calcium-dependent phospholipid binding
GO:0008289--F:lipid binding
GO:0046872--F:metal ion binding
GO:0005543--F:phospholipid binding
GO:0090158--P:endoplasmic reticulum membrane organization
GO:0060304--P:regulation of phosphatidylinositol dephosphorylation