dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016675
Uniprot Accession Q12446; LAS17_YEAST; D6W2N7;
Genbank Protein ID NP_014824.1;
Genbank Nucleotide ID NM_001183600.1;
Protein Name Proline-rich protein LAS17
Protein Synonyms/Alias
Gene Name LAS17
Gene Synonyms/Alias YOR181W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 10
PositionPeptidesSourceReferences ( PMIDs )
160VHGPRGESLIDNQRKcurated25315811
176YNYEDVDTIPTTKHKcurated24961812
332PPPPPMRTTTEGSGVPhosphoGRID 2.019779198
333PPPPMRTTTEGSGVRcurated25315811
334PPPMRTTTEGSGVRLPhosphoGRID 2.0;UniProt;curated19779198; 22817900; 25315811
337MRTTTEGSGVRLPAPPhosphoGRID 2.0;UniProt;curated19779198; 22817900
363PPPHRHVTSNTLNSAPhosphoGRID 2.019779198
380NSLLPQATGRRGPAPPhosphoPep 2.0;curated19060867; 25704821
586LQEARGESASPPAAAdbPTM 3.0;PhosphoGRID 2.0;curated17563356; 16381945; 23193290; 22817900
588EARGESASPPAAAGNdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17563356; 18407956; 16381945; 23193290; 19060867; 19366988;
Sequence
(Fasta)		MGLLNSSDKE IIKRALPKAS NKIIDVTVAR LYIAYPDKNE WQYTGLSGAL ALVDDLVGNT 60
FFLKLVDING HRGVIWDQEL YVNFEYYQDR TFFHTFEMEE CFAGLLFVDI NEASHFLKRV 120
QKRERYANRK TLLNKNAVAL TKKVREEQKS QVVHGPRGES LIDNQRKRYN YEDVDTIPTT 180
KHKAPPPPPP TAETFDSDQT SSFSDINSTT ASAPTTPAPA LPPASPEVRK EETHPKHSLP 240
PLPNQFAPLP DPPQHNSPPQ NNAPSQPQSN PFPFPIPEIP STQSATNPFP FPVPQQQFNQ 300
APSMGIPQQN RPLPQLPNRN NRPVPPPPPM RTTTEGSGVR LPAPPPPPRR GPAPPPPPHR 360
HVTSNTLNSA GGNSLLPQAT GRRGPAPPPP PRASRPTPNV TMQQNPQQYN NSNRPFGYQT 420
NSNMSSPPPP PVTTFNTLTP QMTAATGQPA VPLPQNTQAP SQATNVPVAP PPPPASLGQS 480
QIPQSAPSAP IPPTLPSTTS AAPPPPPAFL TQQPQSGGAP APPPPPQMPA TSTSGGGSFA 540
ETTGDAGRDA LLASIRGAGG IGALRKVDKS QLDKPSVLLQ EARGESASPP AAAGNGGTPG 600
GPPASLADAL AAALNKRKTK VGAHDDMDNG DDW 634
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR011993--PH/PTB_dom
IPR000697--WH1/EVH1_dom
IPR003124--WH2_dom
IPR028297--Wsp1/Las17_fungal
PROSITE

PS50229--WH1
PS51082--WH2
Pfam

PF00568--WH1
PF02205--WH2
Gene Ontology

GO:0030479--C:actin cortical patch
GO:0003779--F:actin binding
GO:0051666--P:actin cortical patch localization
GO:0007015--P:actin filament organization
GO:0030041--P:actin filament polymerization
GO:0045010--P:actin nucleation
GO:0032233--P:positive regulation of actin filament bundle assembly
GO:2000601--P:positive regulation of Arp2/3 complex-mediated actin nucleation