dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0016671
Uniprot Accession Q12441; YD12A_YEAST; D6VSJ4;
Genbank Protein ID NP_620388.3;
Genbank Nucleotide ID NM_001184435.3;
Protein Name Transposon Ty1-DR3 Gag polyprotein
Protein Synonyms/Alias Gag-p49;Transposon Ty1 protein A;TY1A;TYA;p58;
Gene Name TY1A-DR3
Gene Synonyms/Alias YDRCTy1-2 GAG;YDR210C-C;YD8142B.02c;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity).
Phosphorylation Sites
dbPAF PTMs: 10
PositionPeptidesSourceReferences ( PMIDs )
13LSNYPHISHGSACASdbPTM 3.015665377; 16381945; 23193290
404TARAHNVSTSINSPSPhosphoGRID 2.0;PhosphoPep 2.0;curated17563356; 19060867; 22817900
405ARAHNVSTSINSPSTPhosphoGRID 2.0;PhosphoPep 2.0;curated17563356; 19060867; 22817900
406RAHNVSTSINSPSTDPhosphoPep 2.019060867
409NVSTSINSPSTDNDSPhosphoGRID 2.0;PhosphoPep 2.0;curated17563356; 19060867; 26040289; 22817900
411STSINSPSTDNDSISPhosphoPep 2.019060867
412TSINSPSTDNDSISKPhosphoGRID 2.0;PhosphoPep 2.0;curated17563356; 19060867; 22817900
416SPSTDNDSISKSTTEPhosphoPep 2.0;UniProt19060867; 18407956
418STDNDSISKSTTEPIPhosphoPep 2.019060867
421NDSISKSTTEPIQLNPhosphoPep 2.019060867
Sequence
(Fasta)
MESQQLSNYP HISHGSACAS VTSKEVHTNQ DPLDVSASKI QEYDKASTKA NSQQTTTPAS 60
SAVPENPHHA SPQPASVPPP QNGPYPQQCM MTQNQANPSG WSFYGHPSMI PYTPYQMSPM 120
YFPPGPQSQF PQYPSSVGTP LSTPSPESGN TFTDSSSADS DMTSTKKYVR PPPMLTSPND 180
FPNWVKTYIK FLQNSNLGGI IPTVNGKPVR QITDDELTFL YNTFQIFAPS QFLPTWVKDI 240
LSVDYTDIMK ILSKSIEKMQ SDTQEANDIV TLANLQYNGS TPADAFETKV TNIIDRLNNN 300
GIHINNKVAC QLIMRGLSGE YKFLRYTRHR HLNMTVAELF LDIHAIYEEQ QGSRNSKPNY 360
RRNRSDEKND SRSYTNTTKP KVIARNPQKT NNSKSKTARA HNVSTSINSP STDNDSISKS 420
TTEPIQLNNK HDLHLRPETY 441
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0688--Ribosomal frameshifting
KW-0694--RNA-binding
KW-0814--Transposable element

Interpro

IPR015820--Retrotransposon_Ty1A_N

PROSITE
Pfam

PF01021--TYA

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000943--C:retrotransposon nucleocapsid
GO:0003723--F:RNA binding
GO:0032197--P:transposition, RNA-mediated