dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0016667
Uniprot Accession Q12436; ZRT2_YEAST; D6VYC5;
Genbank Protein ID NP_013231.1;
Genbank Nucleotide ID NM_001182017.1;
Protein Name Zinc-regulated transporter 2
Protein Synonyms/Alias Low-affinity zinc transport protein ZRT2;
Gene Name ZRT2
Gene Synonyms/Alias YLR130C;L3120;L9606.9;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Low-affinity zinc transport protein. Active in zinc-replete cells and is time-, temperature- and concentration-dependent and prefers zinc over other metals as its substrate.
Phosphorylation Sites
dbPAF PTMs: 16
PositionPeptidesSourceReferences ( PMIDs )
141GDHGEVTSIDVDAPSPhosphoGRID 2.0;curated19779198; 26040289; 22817900
148SIDVDAPSSGFVIRNPhosphoGRID 2.0;UniProt;curated19779198; 26040289; 22817900
149IDVDAPSSGFVIRNMPhosphoGRID 2.0;UniProt;curated19779198; 22817900
162NMDSDPVSFNNEAAYPhosphoGRID 2.0;UniProt;curated19779198; 26040289; 22369663; 22817900
169SFNNEAAYSIHNDKTPhosphoGRID 2.019779198
170FNNEAAYSIHNDKTPPhosphoGRID 2.0;PhosphoPep 2.0;UniProt;curated19779198; 19060867; 26040289; 25315811
188RNEEIVATPIKEKEPPhosphoGRID 2.0;UniProt;curated19823750; 19795423; 19779198; 26040289; 22369663; 22817900;
209YDLEPGKTESLANELcurated24961812
211LEPGKTESLANELVPcurated24961812
219LANELVPTSSHATNLcurated24961812
220ANELVPTSSHATNLAcurated24961812
221NELVPTSSHATNLASPhosphoGRID 2.0;curated19779198; 22817900; 24961812
224VPTSSHATNLASVPGPhosphoGRID 2.0;curated19779198; 24961812
228SHATNLASVPGKDHYPhosphoGRID 2.019779198
236VPGKDHYSHENDHQDcurated25704821
245ENDHQDVSQLATRIEPhosphoGRID 2.0;curated19779198; 25704821; 22817900; 24961812
Sequence
(Fasta)
MVDLIARDDS VDTCQASNGY NGHAGLRILA VFIILISSGL GVYFPILSSR YSFIRLPNWC 60
FFIAKFFGSG VIVATAFVHL LQPAAEALGD ECLGGTFAEY PWAFGICLMS LFLLFFTEII 120
THYFVAKTLG HDHGDHGEVT SIDVDAPSSG FVIRNMDSDP VSFNNEAAYS IHNDKTPYTT 180
RNEEIVATPI KEKEPGSNVT NYDLEPGKTE SLANELVPTS SHATNLASVP GKDHYSHEND 240
HQDVSQLATR IEEEDKEQYL NQILAVFILE FGIIFHSVFV GLSLSVAGEE FETLFIVLTF 300
HQMFEGLGLG TRVAETNWPE SKKYMPWLMG LAFTLTSPIA VAVGIGVRHS WIPGSRRALI 360
ANGVFDSISS GILIYTGLVE LMAHEFLYSN QFKGPDGLKK MLSAYLIMCC GAALMALLGK 420
WA 423
Keyword

KW-0181--Complete proteome
KW-0406--Ion transport
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
KW-0862--Zinc
KW-0864--Zinc transport

Interpro

IPR003689--ZIP
IPR004698--Zn/Fe_permease_fun/pln

PROSITE
Pfam

PF02535--Zip

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0000007--F:low-affinity zinc ion transmembrane transporter activity
GO:0006831--P:low-affinity zinc II ion transport