dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0016665
Uniprot Accession Q12433; AHC1_YEAST; D6W290;
Genbank Protein ID NP_014666.1;
Genbank Nucleotide ID NM_001183442.1;
Protein Name Protein AHC1
Protein Synonyms/Alias ADA HAT complex component 1;
Gene Name AHC1
Gene Synonyms/Alias YOR023C;OR26.13;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Functions as component of the transcription regulatory histone acetylation (HAT) complex ADA. ADA preferentially acetylates nucleosomal histones H3 (at 'Lys-14' and 'Lys-18') and H2B. AHC1 is required for the overall structural integrity of the ADA complex.
Phosphorylation Sites
 dbPAF PTMs: 14
PositionPeptidesSourceReferences ( PMIDs )
34TNVYQVTTPKSPQDLPhosphoGRID 2.0;curated19779198; 24961812; 20377248
37YQVTTPKSPQDLENNdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19779198; 19366988; 22817900;
196HHHYHTRSKSNGLLLPhosphoGRID 2.0;PhosphoPep 2.019779198; 19060867
198HYHTRSKSNGLLLEPcurated26040289; 22369663; 24961812; 25315811
247HSNSDGISSPRSSSIPhosphoPep 2.019060867
248SNSDGISSPRSSSISPhosphoPep 2.019060867
282LNHRRNYSSTCLTSNPhosphoGRID 2.0;UniProt;curated19779198; 22817900; 25315811
284HRRNYSSTCLTSNSGcurated25315811
391IAIPKPQSPINHSENcurated24961812
457QKEQEEESSKSDDEAcurated20377248
458KEQEEESSKSDDEAScurated22817900; 20377248
505LLRKRKLSLNSSTPMdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated17287358; 18407956; 16381945; 23193290; 20702584; 19779198;
510KLSLNSSTPMEDLPLdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
551DPAAKSSSYYNLRSKcurated22369663
Sequence
(Fasta)		MMSPAQDKLQ HQHHNPNSSS SSSSKMTNVY QVTTPKSPQD LENNMDEPFK MDTATSNPDK 60
DSENTQRLKY ECAKGEIQNV LNLHIMLNHK HVRHLRRNVQ KVNAKLALLE TLHKDTGLLN 120
KIERTYQLKI KQHQQHSVLG GHFHDSTATE NTNASNYNLS YPVLSDYNIN CQPLSSSSNR 180
NLSTTRIPHH HYHTRSKSNG LLLEPSALRP ANSNIIDYRL TGSKSLSEAI TKPTPVSLPH 240
SNSDGISSPR SSSISPLDEQ PGFQILPFKP SQMHLNHRRN YSSTCLTSNS GIIGKTENNE 300
PIFRRYDGIL VIITCSKCDR SGFTSAQGIV NHTRLKHSKL YSSQPLAVLN NQKLLPNDKQ 360
DPEILSKFKK LNLDPNKDYL PSDIAIPKPQ SPINHSENHT RAPKTVKNTP HLEKLYQNKE 420
DFKKLIDMVN ETPDDLNEYL KQREIQLRYQ KEQEEESSKS DDEASYVPSP SLSATATTTT 480
TTDPPSPPVL SSSLQRKLLR KRKLSLNSST PMEDLPLRER LRANPTDKKP RKAALLTNEL 540
EGPDPAAKSS SYYNLRSKSR LRGSHT 567
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
Interpro

IPR015880--Znf_C2H2-like
PROSITE
Pfam
Gene Ontology

GO:0005671--C:Ada2/Gcn5/Ada3 transcription activator complex
GO:0005737--C:cytoplasm
GO:0016573--P:histone acetylation
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated