dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0016647
Uniprot Accession Q12400; TRM10_YEAST; D6W1X5;
Genbank Protein ID NP_014548.1;
Genbank Nucleotide ID NM_001183347.1;
Protein Name tRNA (guanine(9)-N1)-methyltransferase
Protein Synonyms/Alias tRNA methyltransferase 10;tRNA(m1G9)-methyltransferase;tRNA(m1G9)MTase;
Gene Name TRM10
Gene Synonyms/Alias YOL093W;O0926;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
S-adenosyl-L-methionine-dependent guanine N(1)-methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in cytoplasmic tRNAs.
Phosphorylation Sites
dbPAF PTMs: 9
PositionPeptidesSourceReferences ( PMIDs )
2------MSNDEINQNdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;SysPTM 2.0;curated18407956; 16381945; 23193290; 21126336; 21081558; 19366988;
16NEEKVKRTPPLPPVPdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 21126336; 19779198; 19366988;
179MFGDEHISKDKIVYLcurated22817900
187KDKIVYLTADTEEKLcurated22817900
190IVYLTADTEEKLEKLcurated22817900
283KLDAEAKSASSSPAPPhosphoGRID 2.0;UniProt;curated20702584; 19779198; 22817900; 24961812; 25315811
285DAEAKSASSSPAPKDPhosphoGRID 2.0;curated20702584; 22817900; 24961812
286AEAKSASSSPAPKDTPhosphoGRID 2.0;curated20702584; 22817900; 24961812
287EAKSASSSPAPKDT-PhosphoGRID 2.0;curated19779198; 22817900; 24961812
Sequence
(Fasta)
MSNDEINQNE EKVKRTPPLP PVPEGMSKKQ WKKMCKRQRW EENKAKYNAE RRVKKKRLRH 60
ERSAKIQEYI DRGEEVPQEL IREPRINVNQ TDSGIEIILD CSFDELMNDK EIVSLSNQVT 120
RAYSANRRAN HFAEIKVAPF DKRLKQRFET TLKNTNYENW NHFKFLPDDK IMFGDEHISK 180
DKIVYLTADT EEKLEKLEPG MRYIVGGIVD KNRYKELCLK KAQKMGIPTR RLPIDEYINL 240
EGRRVLTTTH VVQLMLKYFD DHNWKNAFES VLPPRKLDAE AKSASSSPAP KDT 294
Keyword

KW-0002--3D-structure
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0819--tRNA processing

Interpro

IPR028564--MT_TRM10-typ
IPR007356--tRNA_m1G_MeTrfase_euk
IPR016653--tRNA_MeTfrase_TRM10
IPR016009--tRNA_MeTrfase_TRMD/TRM10

PROSITE

PS51675--SAM_MT_TRM10

Pfam

PF01746--tRNA_m1G_MT

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005654--C:nucleoplasm
GO:0052905--F:tRNA (guanine(9)-N(1))-methyltransferase activity
GO:0016423--F:tRNA (guanine) methyltransferase activity
GO:0030488--P:tRNA methylation