dbPAF Protein Information
| Tag | Content | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0016642 | ||||||||||||||||
| Uniprot Accession | Q12387; NAA25_YEAST; D6W1Z2; | ||||||||||||||||
| Genbank Protein ID | NP_014566.1; | ||||||||||||||||
| Genbank Nucleotide ID | NM_001183330.1; | ||||||||||||||||
| Protein Name | N-terminal acetyltransferase B complex subunit MDM20 | ||||||||||||||||
| Protein Synonyms/Alias | |||||||||||||||||
| Gene Name | MDM20 | ||||||||||||||||
| Gene Synonyms/Alias | DEC1;YOL076W; | ||||||||||||||||
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) | ||||||||||||||||
| NCBI Taxa ID | 559292 | ||||||||||||||||
| Functional Description (View all) |
Non-catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes acetylation of the amino-terminal methionine residues of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met. NatB acetylates TPM1 protein and regulates tropomyocin-actin interactions. MDM20 is required for mitochondrial inheritance during budding and together with TPM1, is essential for the integrity and assembly of actin cables. Genetically interacts with CIN8. | ||||||||||||||||
| Phosphorylation Sites |
dbPAF PTMs: 3
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| Sequence (Fasta) | MSDKIQEEIL GLVSRSNFKQ CYAKLGQLQK QFPNALYFKI LETYVKFKQS PGKFDYNKLL 60 EEPYGLKGTT ITGDTRSLEF LHNFFVELGK YDEALHVYER GNFKFPSYEL SYHWFMKALE 120 DSNYNQMSKA SLQLAKYSDS GNLPKRAYYF WNAISILAVS RFQENTLSDP KKILLSRLAR 180 QSLLDLKPFQ NVQEIIVYCL VLDELFPQSR EISEEIVAIT FANFDTSVNL YLKNFILKHT 240 KLLNSPQKLF EVCSKLIEKG LDDYELITNL IDAAYKLSKS KDEVKQWIDE NLGDSRNTRL 300 ARLKLDIMYT DSVSESSLSY YLSKYHNKPC CSIDLNHYSG HINIDMLKSI MSKYDPEDKD 360 LIHHCNILEL GLIGSDSINN YNKFKGTLEK KSVTDYSSCS TFLLEIVKDK CKKTNPELKD 420 VLLCITILEN YQAKDPHNFD TMCWLIVLYM YLGLVPDAYF HFINLKIKNV QTDSLDYMIF 480 SRFSTLFPNK QSDFYSKTFH EHNNLYDTSL ANLPRYIQVA FERNSYSKIL GMLEMRDKLM 540 KSYTRWTKTL ENLQFSRLCN DKRGHLLQKL HEDWRSLEMT QSVSFSDNRD FSILDENFAQ 600 FLNRGKILEY ANLNEESIFL TLIRELIIEA LPNGEKTEQI SALLKKLPSI NLEELLNNNL 660 TEVESASFLI FFEIYENNGK NLHDLISRLM KVPINAKQNW MVSHTYLTKM ATLKTLDSLK 720 RIKDKEIQKL IKNSLKELRS CCDDVFKGYS KALVQAYEEL KKDECGNLLK ELDVKAENVK 780 NIKNSLLGIQ KSVRNL 797 |
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| Keyword | KW-0007--Acetylation |
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| Interpro | IPR019183--N-acetylTrfase_B_cplx_non-cat |
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| PROSITE | |||||||||||||||||
| Pfam | PF09797--NatB_MDM20 |
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| Gene Ontology | GO:0031415--C:NatA complex |