dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0016637 | ||||||||
| Uniprot Accession | Q12381; PRP1_SCHPO; | ||||||||
| Genbank Protein ID | NP_596086.1; | ||||||||
| Genbank Nucleotide ID | NM_001022000.2; | ||||||||
| Protein Name | Pre-mRNA-splicing factor prp1 | ||||||||
| Protein Synonyms/Alias | |||||||||
| Gene Name | prp1 | ||||||||
| Gene Synonyms/Alias | zer1;SPBC6B1.07; | ||||||||
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) | ||||||||
| NCBI Taxa ID | 284812 | ||||||||
| Functional Description (View all) |
Involved in pre-mRNA splicing. Interacts with prp6 and prp13. May also be involved in the regulation of the G0-G1/G2 transition. Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site-3' splice 3'-exon region. | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
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| Sequence (Fasta) | MANFYPDFLN MQPPPNYVAG LGRGATGFTT RSDLGPAQEL PSQESIKAAI EQRKSEIEEE 60 EDIDPRYQDP DNEVALFATA PYDHEDEEAD KIYQSVEEHL SKRRKSQREK QEQLQKEKYE 120 KENPKVSSQF ADLKRGLSTL TDEDWNNIPE PGDLTRKKRT KQPRRERFYA TSDFVLASAR 180 NENQAISNFA VDTQAGTETP DMNGTKTNFV EIGAARDKVL GIKLAQASSN LTSPSTIDPK 240 GYLTSLNSMV PKNANDLGDI RKARKLLQSV IETNPKHASG WVAAARLEEV ANKLSQAQSL 300 ILKGCENCSR SEDVWLEAIR LHPAAEAKVI IANAVKKLPK SVTLWLEAEK LENQAQHKKR 360 IIKKALEFNP TSVSLWKEAV NLEEEVDNAR ILLARAVELI PMSIDLWLAL ARLETYENAK 420 KVLNKARQTI RTSHEVWIAA ARLEEQQGNV SRVEKIMARG VSELQATGGM LQRDQWLSEA 480 EKCETEGAVI TAQAIINTCL GVGLDEEDQF DTWLDDAQSF IARKCIDCAR AVFAFSLRVY 540 PKSEKLWLRA VELEKLYGTT ESVCSILEKA VESCPKAEIL WLLYAKERKN VNDIAGARNI 600 LGRAFEYNSN SEEIWLAAVR IEFVNNENER ARKLLARARI ESGTERIWTK SISLERILDE 660 KDRALQLLEN ALKIYPHYDK LYMMKGQIFE DKEQIELARD AYLAGTKVCP YSIPLWLLLA 720 KLEEKQSVIR ARVVFDRAKV KNPKNEFLWL ELIKMELRAG NISQVRAALA KALQECPSSG 780 LLWTEAIWLE PRAQRKTRAT DALRKCEGNA HLLCTIARML WLEKKADKAR SWFLKAVKAD 840 QDNGDVWCWF YKYSLEAGNE DQQKEVLTSF ETADPHHGYF WPSITKDIKN SRKTPQELLH 900 LAINVL 907 |
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| Keyword | KW-0181--Complete proteome |
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| Interpro | IPR003107--HAT |
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| PROSITE | |||||||||
| Pfam | |||||||||
| Gene Ontology | GO:0005634--C:nucleus |