| Tag |
Content |
| dbPAF ID |
dbPAF-0016635 |
| Uniprot Accession |
Q12377; RPN6_YEAST; D6VRQ3;
|
| Genbank Protein ID |
NP_010186.1;
|
| Genbank Nucleotide ID |
NM_001180156.1;
|
| Protein Name |
26S proteasome regulatory subunit RPN6 |
| Protein Synonyms/Alias |
Proteasome non-ATPase subunit 4; |
| Gene Name |
RPN6 |
| Gene Synonyms/Alias |
NAS4;YDL097C;D2381; |
| Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID |
559292 |
Functional Description
(View all) |
Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, RPN6 is required for proteasome assembly.Functional Description
Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, RPN6 is required for proteasome assembly. |
Phosphorylation Sites
|
dbPAF PTMs: 6 |
Sequence
(Fasta) | MSLPGSKLEE ARRLVNEKQY NEAEQVYLSL LDKDSSQSSA AAGASVDDKR RNEQETSILE 60
LGQLYVTMGA KDKLREFIPH STEYMMQFAK SKTVKVLKTL IEKFEQVPDS LDDQIFVCEK 120
SIEFAKREKR VFLKHSLSIK LATLHYQKKQ YKDSLALIND LLREFKKLDD KPSLVDVHLL 180
ESKVYHKLRN LAKSKASLTA ARTAANSIYC PTQTVAELDL MSGILHCEDK DYKTAFSYFF 240
ESFESYHNLT THNSYEKACQ VLKYMLLSKI MLNLIDDVKN ILNAKYTKET YQSRGIDAMK 300
AVAEAYNNRS LLDFNTALKQ YEKELMGDEL TRSHFNALYD TLLESNLCKI IEPFECVEIS 360
HISKIIGLDT QQVEGKLSQM ILDKIFYGVL DQGNGWLYVY ETPNQDATYD SALELVGQLN 420
KVVDQLFEKA SVLY
435Fasta Sequence
>Q12377|RPN6|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
MSLPGSKLEEARRLVNEKQYNEAEQVYLSLLDKDSSQSSAAAGASVDDKRRNEQETSILELGQLYVTMGAKDKLREFIPHSTEYMMQFAKSKTVKVLKTLIEKFEQVPDSLDDQIFVCEKSIEFAKREKRVFLKHSLSIKLATLHYQKKQYKDSLALINDLLREFKKLDDKPSLVDVHLLESKVYHKLRNLAKSKASLTAARTAANSIYCPTQTVAELDLMSGILHCEDKDYKTAFSYFFESFESYHNLTTHNSYEKACQVLKYMLLSKIMLNLIDDVKNILNAKYTKETYQSRGIDAMKAVAEAYNNRSLLDFNTALKQYEKELMGDELTRSHFNALYDTLLESNLCKIIEPFECVEISHISKIIGLDTQQVEGKLSQMILDKIFYGVLDQGNGWLYVYETPNQDATYDSALELVGQLNKVVDQLFEKASVLY
|
| Keyword |
KW-0002--3D-structure
KW-0007--Acetylation
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0647--Proteasome
KW-1185--Reference proteome
|
| Interpro |
IPR013143--PAM
IPR000717--PCI_dom
IPR011990--TPR-like_helical_dom
IPR011991--WHTH_DNA-bd_dom
|
| PROSITE |
|
| Pfam |
PF01399--PCI
|
| Gene Ontology |
GO:0008541--C:proteasome regulatory particle, lid subcomplex
GO:0034515--C:proteasome storage granule
GO:0005198--F:structural molecule activity
GO:0043248--P:proteasome assembly
GO:0006511--P:ubiquitin-dependent protein catabolic process
|
